6N3I
 
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8Y66
 | | Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin | | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Solute carrier family 2, facilitated glucose transporter member 9 | | 著者 | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | | 登録日 | 2024-02-01 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Structural basis for urate recognition and apigenin inhibition of human GLUT9.
Nat Commun, 15, 2024
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8Y65
 | | Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate | | 分子名称: | Solute carrier family 2, facilitated glucose transporter member 9, URIC ACID | | 著者 | Pan, X.J, Shen, Z.L, Xu, L, Huang, G.X.Y. | | 登録日 | 2024-02-01 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Structural basis for urate recognition and apigenin inhibition of human GLUT9.
Nat Commun, 15, 2024
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8BVS
 | | Cryo-EM structure of rat SLC22A6 bound to tenofovir | | 分子名称: | CHLORIDE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody), ... | | 著者 | Parker, J.L, Kato, T, Newstead, S. | | 登録日 | 2022-12-05 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
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8BVR
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8BVT
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8BW7
 | | Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid | | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, Solute carrier family 22 member 6, ... | | 著者 | Parker, J.L, Kato, T, Newstead, S. | | 登録日 | 2022-12-06 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
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8ET7
 | | Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1 | | 著者 | Suo, Y, Wright, N.J, Lee, S.-Y. | | 登録日 | 2022-10-16 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
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8ET8
 | | Cryo-EM structure of the organic cation transporter 1 in complex with verapamil | | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1 | | 著者 | Suo, Y, Wright, N.J, Lee, S.-Y. | | 登録日 | 2022-10-16 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
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8ET9
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8ET6
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4ZWB
 | | Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom | | 分子名称: | Solute carrier family 2, facilitated glucose transporter member 3, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | | 登録日 | 2015-05-19 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
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4YB9
 | | Crystal structure of the Bovine Fructose transporter GLUT5 in an open inward-facing conformation | | 分子名称: | Solute carrier family 2, facilitated glucose transporter member 5 | | 著者 | Verdon, G, Kang, H.J, Iwata, S, Drew, D. | | 登録日 | 2015-02-18 | | 公開日 | 2015-10-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure and mechanism of the mammalian fructose transporter GLUT5.
Nature, 526, 2015
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4YBQ
 | | Rat GLUT5 with Fv in the outward-open form | | 分子名称: | Solute carrier family 2, facilitated glucose transporter member 5, antibody Fv fragment heavy chain, ... | | 著者 | Nomura, N, Shimamura, T, Iwata, S. | | 登録日 | 2015-02-19 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Structure and mechanism of the mammalian fructose transporter GLUT5
Nature, 526, 2015
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4ZWC
 | | Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | | 登録日 | 2015-05-19 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
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4ZW9
 | | Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5 angstrom | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Solute carrier family 2, facilitated glucose transporter member 3, ... | | 著者 | Deng, D, Sun, P.C, Yan, C.Y, Yan, N. | | 登録日 | 2015-05-19 | | 公開日 | 2015-07-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | Molecular basis of ligand recognition and transport by glucose transporters
Nature, 526, 2015
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5C65
 | | Structure of the human glucose transporter GLUT3 / SLC2A3 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Octyl Glucose Neopentyl Glycol, Solute carrier family 2, ... | | 著者 | Pike, A.C.W, Quigley, A, Chu, A, Tessitore, A, Xia, X, Mukhopadhyay, S, Wang, D, Kupinska, K, Strain-Damerell, C, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2015-06-22 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of the human glucose transporter GLUT3 / SLC2A3
To Be Published
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8SC3
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8SC4
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8SDU
 | | Structure of rat organic anion transporter 1 (OAT1) | | 分子名称: | Solute carrier family 22 member 6 | | 著者 | Dou, T, Jiang, J. | | 登録日 | 2023-04-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (2.05 Å) | | 主引用文献 | The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.
Nat.Struct.Mol.Biol., 30, 2023
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8SDZ
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8SC1
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8SC2
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8SC6
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8SDY
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