8Y66
Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin
Summary for 8Y66
Entry DOI | 10.2210/pdb8y66/pdb |
EMDB information | 38968 |
Descriptor | Solute carrier family 2, facilitated glucose transporter member 9, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one (2 entities in total) |
Functional Keywords | glut9, inhibitor, apigenin, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 63485.33 |
Authors | |
Primary citation | Shen, Z.,Xu, L.,Wu, T.,Wang, H.,Wang, Q.,Ge, X.,Kong, F.,Huang, G.,Pan, X. Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15:5039-5039, 2024 Cited by PubMed: 38866775DOI: 10.1038/s41467-024-49420-9 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.28 Å) |
Structure validation
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