8Y66

Cryo-EM structure of human urate transporter GLUT9 bound to inhibitor apigenin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Solute carrier family 2, facilitated glucose transporter member 9	polymer	582	63215.1	1	UniProt (Q9NRM0) Pfam (PF00083) In PDB	Homo sapiens (human)	Glucose transporter type 9,GLUT-9,Urate transporter
2	A	5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one	non-polymer		270.2	1	Chemie (AGI)

Sequence modifications

A: 2 - 540 (UniProt: Q9NRM0)

PDB	External Database	Details
Met -41	-	initiating methionine
Ala -40	-	expression tag
Ser -39	-	expression tag
Trp -38	-	expression tag
Ser -37	-	expression tag
His -36	-	expression tag
Pro -35	-	expression tag
Gln -34	-	expression tag
Phe -33	-	expression tag
Glu -32	-	expression tag
Lys -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Gly -28	-	expression tag
Ala -27	-	expression tag
Arg -26	-	expression tag
Gly -25	-	expression tag
Gly -24	-	expression tag
Ser -23	-	expression tag
Gly -22	-	expression tag
Gly -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Trp -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
Pro -15	-	expression tag
Gln -14	-	expression tag
Phe -13	-	expression tag
Glu -12	-	expression tag
Lys -11	-	expression tag
Gly -10	-	expression tag
Phe -9	-	expression tag
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Lys -1	-	expression tag
Gly 0	-	expression tag
Thr 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63215.1
Non-Polymers*	Number of molecules	1
	Total formula weight	270.2
All*	Total formula weight	63485.3

*Water molecules are not included.