8Y65

Cryo-EM structure of human urate transporter GLUT9 bound to substrate urate

Summary for 8Y65

Entry DOI	10.2210/pdb8y65/pdb
EMDB information	38966
Descriptor	Solute carrier family 2, facilitated glucose transporter member 9, URIC ACID (2 entities in total)
Functional Keywords	glut9, urate, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	63383.20
Authors	Pan, X.J.,Shen, Z.L.,Xu, L.,Huang, G.X.Y. (deposition date: 2024-02-01, release date: 2024-06-19)
Primary citation	Shen, Z.,Xu, L.,Wu, T.,Wang, H.,Wang, Q.,Ge, X.,Kong, F.,Huang, G.,Pan, X. Structural basis for urate recognition and apigenin inhibition of human GLUT9. Nat Commun, 15:5039-5039, 2024 Cited by PubMed: 38866775 DOI: 10.1038/s41467-024-49420-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.51 Å)

Structure validation