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PDB: 16 件
1LK2
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BU of 1lk2 by Molmil
1.35A crystal structure of H-2Kb complexed with the GNYSFYAL peptide
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Luz, J.G, Rudolph, M.G, Wilson, I.A, Eisen, H.
登録日2002-04-23
公開日2003-11-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.
J.Immunol., 172, 2004
7SL7
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BU of 7sl7 by Molmil
Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R)
分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ...
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL3
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BU of 7sl3 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL1
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BU of 7sl1 by Molmil
Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STH
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BU of 7sth by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
8DTM
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BU of 8dtm by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 component 2
分子名称: Insulin mimetic peptide S597 component 2, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-26
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
7SL2
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BU of 7sl2 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL6
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BU of 7sl6 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
8EZ0
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BU of 8ez0 by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Symmetric conformation
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
7STK
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BU of 7stk by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STJ
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BU of 7stj by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
8EYX
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BU of 8eyx by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 1
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
8EYY
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BU of 8eyy by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S, denoted as IR-3CS) Asymmetric conformation 2
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
7STI
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BU of 7sti by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7SL4
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BU of 7sl4 by Molmil
Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation
分子名称: Insulin A chain, Insulin B chain, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-10-22
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
8DTL
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BU of 8dtl by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 peptide
分子名称: Insulin mimetic peptide S597, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-25
公開日2022-09-07
最終更新日2022-10-12
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022

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件を2024-07-10に公開中

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