8BN3
 
 | | Yeast 80S, ES7s delta, eIF5A, Stm1 containing | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | 著者 | Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N. | | 登録日 | 2022-11-12 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes.
Nucleic Acids Res., 52, 2024
|
|
6TB3
 | | yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex | | 分子名称: | 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R. | | 登録日 | 2019-10-31 | | 公開日 | 2020-04-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
|
|
6Q8Y
 | | Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Heckel, E, Cheng, J, Buschauer, R, Kater, L, Berninghausen, O, Becker, T, Beckmann, R. | | 登録日 | 2018-12-16 | | 公開日 | 2019-03-13 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the 80S ribosome-Xrn1 nuclease complex.
Nat.Struct.Mol.Biol., 26, 2019
|
|
6HHQ
 | | Crystal structure of compound C45 bound to the yeast 80S ribosome | | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | | 登録日 | 2018-08-28 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Nucleic Acids Res., 47, 2019
|
|
5ON6
 | | Crystal structure of haemanthamine bound to the 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Pellegrino, S, Meyer, M, Yusupova, G, Yusupov, M. | | 登録日 | 2017-08-03 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.10000229 Å) | | 主引用文献 | The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth.
Structure, 26, 2018
|
|
6T7I
 | | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | | 登録日 | 2019-10-22 | | 公開日 | 2019-12-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
|
|
6S47
 | | Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1 | | 分子名称: | 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V. | | 登録日 | 2019-06-26 | | 公開日 | 2019-07-24 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
|
|
7B7D
 | | Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N. | | 登録日 | 2020-12-10 | | 公開日 | 2021-03-10 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome
To Be Published
|
|
5NDV
 | | Crystal structure of Paromomycin bound to the yeast 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | | 登録日 | 2017-03-09 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5M1J
 | | Nonstop ribosomal complex bound with Dom34 and Hbs1 | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | | 登録日 | 2016-10-07 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
|
|
6Z6J
 | | Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition | | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | | 著者 | Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | 登録日 | 2020-05-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
|
|
5MEI
 | | Crystal structure of Agelastatin A bound to the 80S ribosome | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | McClary, B, Zinshteyn, B, Meyer, M, Jouanneau, M, Pellegrino, S, Yusupova, G, Schuller, A, Reyes, J.C.P, Lu, J, Luo, C, Dang, Y, Romo, D, Yusupov, M, Green, R, Liu, J.O. | | 登録日 | 2016-11-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A.
Cell Chem Biol, 24, 2017
|
|
6GQB
 | | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-07-11 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
|
|
6GQV
 | | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | | 登録日 | 2018-06-08 | | 公開日 | 2018-07-11 | | 最終更新日 | 2018-08-08 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
|
|
4V8Y
 | | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | | 分子名称: | 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... | | 著者 | Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. | | 登録日 | 2013-07-20 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
|
|
7NRD
 | | Structure of the yeast Gcn1 bound to a colliding stalled 80S ribosome with MBF1, A/P-tRNA and P/E-tRNA | | 分子名称: | 25S rRNA (3184-MER), 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Pochopien, A.A, Beckert, B, Wilson, D.N. | | 登録日 | 2021-03-03 | | 公開日 | 2021-04-14 | | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | | 主引用文献 | Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6GQ1
 | | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Pellegrino, S, Demeshkina, N, Mancera-Martinez, E, Melnikov, S, Simonetti, A, Myasnikov, A, Yusupov, M, Yusupova, G, Hashem, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-07-11 | | 最終更新日 | 2018-08-08 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
|
|
6I7O
 | | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition. | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | 著者 | Tesina, P, Cheng, J, Becker, T, Beckmann, R. | | 登録日 | 2018-11-16 | | 公開日 | 2019-01-16 | | 最終更新日 | 2019-03-13 | | 実験手法 | ELECTRON MICROSCOPY (5.3 Å) | | 主引用文献 | Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
|
|
4V8Z
 | | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | | 分子名称: | 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... | | 著者 | Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. | | 登録日 | 2013-07-20 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (6.6 Å) | | 主引用文献 | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
|
|
