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PDB: 534 件

7RBR
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BU of 7rbr by Molmil
The crystal structure of Papain-Like Protease of SARS CoV-2, C111S mutant, in complex with a Lys48-linked di-ubiquitin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Papain-like protease, ...
著者Osipiuk, J, Tesar, C, Endres, M, Lanham, B.T, Wydorski, P, Fushman, D, Joachimiak, L, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2021-07-06
公開日2021-09-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin.
Nat Commun, 14, 2023
3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
著者Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
登録日2010-04-08
公開日2010-04-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
8BS9
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BU of 8bs9 by Molmil
Structure of USP36 in complex with Ubiquitin-PA
分子名称: Polyubiquitin-B, SODIUM ION, Ubiquitin carboxyl-terminal hydrolase 36, ...
著者O'Dea, R, Gersch, M.
登録日2022-11-24
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36.
Nat.Chem.Biol., 19, 2023
4WZP
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BU of 4wzp by Molmil
Ser65 phosphorylated ubiquitin, major conformation
分子名称: SULFATE ION, ubiquitin
著者Wauer, T, Wagstaff, J, Freund, S.M.V, Komander, D.
登録日2014-11-20
公開日2015-01-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
Embo J., 34, 2015
3ZNZ
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BU of 3znz by Molmil
Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin
分子名称: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3B0A
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BU of 3b0a by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, TRIS(HYDROXYETHYL)AMINOMETHANE, ...
著者Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
登録日2011-06-07
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
6GZS
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BU of 6gzs by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to ubiquitin
分子名称: Deubiquitinase and deneddylase Dub1, GLYCEROL, Polyubiquitin-B, ...
著者Pruneda, J.N, Komander, D.
登録日2018-07-05
公開日2018-11-14
最終更新日2018-12-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
5CVM
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BU of 5cvm by Molmil
USP46~ubiquitin BEA covalent complex
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
著者Harris, S.F, Yin, J.
登録日2015-07-27
公開日2015-10-07
最終更新日2015-11-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
3H7P
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BU of 3h7p by Molmil
Crystal structure of K63-linked di-ubiquitin
分子名称: CADMIUM ION, Ubiquitin
著者Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J.
登録日2009-04-28
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture.
Proteins, 77, 2009
4LDT
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BU of 4ldt by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ...
著者Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C.
登録日2013-06-25
公開日2013-08-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
3TMP
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BU of 3tmp by Molmil
The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde
分子名称: OTU domain-containing protein 5, Polyubiquitin-C
著者Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A.
登録日2011-08-31
公開日2012-01-11
最終更新日2012-02-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nat.Struct.Mol.Biol., 19, 2012
5D0M
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BU of 5d0m by Molmil
Structure of UbE2D2:RNF165:Ub complex
分子名称: PHOSPHATE ION, Polyubiquitin-B, RING finger protein 165, ...
著者Wright, J.D, Day, C.L, Mace, P.D.
登録日2015-08-03
公開日2015-12-09
最終更新日2016-01-20
実験手法X-RAY DIFFRACTION (1.913 Å)
主引用文献Secondary ubiquitin-RING docking enhances Arkadia and Ark2C E3 ligase activity.
Nat.Struct.Mol.Biol., 23, 2016
5GOH
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BU of 5goh by Molmil
Lys33-linked di-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y, Liu, L.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
3VUW
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BU of 3vuw by Molmil
Crystal structure of A20 ZF7 in complex with linear ubiquitin, form I
分子名称: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ...
著者Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-07-09
公開日2013-02-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31, 2012
2JF5
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BU of 2jf5 by Molmil
crystal structure of Lys63-linked di-ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, COBALT (II) ION, ...
著者Komander, D, Odenwaelder, P, Barford, D.
登録日2007-01-26
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
6N6R
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BU of 6n6r by Molmil
Crystal structure of ABIN-1 UBAN in complex with two M1-linked di-ubiquitins
分子名称: TNFAIP3-interacting protein 1, Ubiquitin
著者Rahighi, S, Dikic, I, Wakatsuki, S.
登録日2018-11-27
公開日2019-07-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains.
J.Mol.Biol., 431, 2019
5ULH
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BU of 5ulh by Molmil
Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, GLYCEROL, THIOCYANATE ION, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
4MSQ
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BU of 4msq by Molmil
Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 catalytic domain bound to ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ...
著者Shrestha, R.K, Ronau, J.A, Das, C.
登録日2013-09-18
公開日2014-06-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
3HM3
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BU of 3hm3 by Molmil
The Structure and conformation of Lys-63 linked tetra-ubiquitin
分子名称: Ubiquitin, ZINC ION
著者Datta, A.B, Hura, G.L, Wolberger, C.
登録日2009-05-28
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献The structure and conformation of Lys63-linked tetraubiquitin.
J.Mol.Biol., 392, 2009
5NL5
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BU of 5nl5 by Molmil
Crystal structure of Zn1.7-E16V human ubiquitin (hUb) mutant adduct, from a solution 70 mM zinc acetate/1.3 mM E16V hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Polyubiquitin-B, ...
著者Fermani, S, Falini, G.
登録日2017-04-04
公開日2017-04-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.
Chemistry, 24, 2018
6ULH
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BU of 6ulh by Molmil
Structure of MavC in complex with its substrate in R3 spacegroup
分子名称: LPG2147 (MavC), Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Iyer, S, Puvar, K, Das, C.
登録日2019-10-08
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
5KYE
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BU of 5kye by Molmil
Crystal structure of USP7 catalytic domain [H294E] mutant in complex with ubiquitin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Rouge, L, Ozen, A.
登録日2016-07-21
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Selectively Modulating Conformational States of USP7 Catalytic Domain for Activation.
Structure, 26, 2018
5GOG
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BU of 5gog by Molmil
Lys29-linked di-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.977 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
3VUY
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BU of 3vuy by Molmil
Crystal structure of A20 ZF7 in complex with linear tetraubiquitin
分子名称: POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ...
著者Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-07-09
公開日2013-02-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31, 2012
5JBY
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BU of 5jby by Molmil
Lys27-linked triubiquitin
分子名称: D-ubiquitin, ubiquitin
著者Pan, M, Gao, S, Zheng, Y.
登録日2016-04-14
公開日2016-07-20
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.987 Å)
主引用文献Structure of Lys27-linked triubiquitin
To Be Published

222415

件を2024-07-10に公開中

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