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PDB: 541 件

5EMZ
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BU of 5emz by Molmil
Crystal structure of K48-linked diubiquitin with F45W mutation in the proximal unit
分子名称: Polyubiquitin-B, SULFATE ION
著者Nakasone, M.A, Paukstelis, P.J, Fushman, D.
登録日2015-11-07
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural characterization and practical fluorescence applications of the F45W ubiquitin mutant
To Be Published
5AF5
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BU of 5af5 by Molmil
Structure of Lys33-linked triUb S.G. P 212121
分子名称: POLYUBIQUITIN-C
著者Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
登録日2015-01-19
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
3VUX
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BU of 3vux by Molmil
Crystal structure of A20 ZF7 in complex with linear ubiquitin, form II
分子名称: 1,2-ETHANEDIOL, POTASSIUM ION, Polyubiquitin-C, ...
著者Nishimasu, H, Ishitani, R, Nureki, O.
登録日2012-07-09
公開日2013-02-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31, 2012
6B7M
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BU of 6b7m by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) in complex with Ubiquitin
分子名称: Polyubiquitin-C, SdeD (lpg2509)
著者Mao, Y, Akturk, A, Wasilko, J.
登録日2017-10-04
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
6HPR
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BU of 6hpr by Molmil
Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub
分子名称: Baculoviral IAP repeat-containing protein 2, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ...
著者Patel, A, Huang, D.T.
登録日2018-09-21
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex.
J. Biol. Chem., 294, 2019
5NMC
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BU of 5nmc by Molmil
Crystal structure of Zn3-hUb(human ubiquitin) adduct from a solution 70 mM zinc acetate/20% v/v TFE/1.3 mM hUb
分子名称: ACETATE ION, Polyubiquitin-C, ZINC ION
著者Fermani, S, Falini, G.
登録日2017-04-05
公開日2017-05-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Aggregation Pathways of Native-Like Ubiquitin Promoted by Single-Point Mutation, Metal Ion Concentration, and Dielectric Constant of the Medium.
Chemistry, 24, 2018
8E7O
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BU of 8e7o by Molmil
CRYSTAL STRUCTURE OF LYS48-LINKED TETRAUBIQUITIN
分子名称: SULFATE ION, Ubiquitin
著者Lemma, B.E, Fushman, D.
登録日2022-08-24
公開日2022-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14, 2023
3V6C
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BU of 3v6c by Molmil
Crystal Structure of USP2 in complex with mutated ubiquitin
分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ...
著者Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2011-12-19
公開日2012-12-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of USP2 in complex with mutated ubiquitin
To be Published
3B08
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BU of 3b08 by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ...
著者Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
登録日2011-06-07
公開日2011-12-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
4I6N
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BU of 4i6n by Molmil
Crystal structure of Trichinella spiralis UCH37 catalytic domain bound to Ubiquitin vinyl methyl ester
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, METHYL 4-AMINOBUTANOATE, SODIUM ION, ...
著者Morrow, M.E, Ronau, J.A, White, R.R, Artavanis-Tsakonas, K, Das, C.
登録日2012-11-29
公開日2013-05-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
Biochemistry, 52, 2013
3NS8
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BU of 3ns8 by Molmil
Crystal structure of an open conformation of Lys48-linked diubiquitin at pH 7.5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Ubiquitin
著者Zhang, D, LaRonde-LeBlanc, N, Fushman, D.
登録日2010-07-01
公開日2011-07-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and biochemical studies of the open state of Lys48-linked diubiquitin.
Biochim.Biophys.Acta, 1823, 2012
7OWD
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BU of 7owd by Molmil
Structure of CYLD CAP-Gly3 (467-552) bound to Ub; tetragonal space group
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase CYLD
著者Elliott, P.R, Komander, D.
登録日2021-06-17
公開日2021-10-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Cell Rep, 37, 2021
4ZFR
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BU of 4zfr by Molmil
Catalytic domain of Sst2 F403A mutant bound to ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, ZINC ION, ...
著者Shrestha, R.K.
登録日2015-04-21
公開日2015-10-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structure of Catalytic domain of Sst2 F403A mutant bound to ubiquitin at 1.7 Angstroms
To Be Published
8ADB
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BU of 8adb by Molmil
Viral tegument-like DUBs
分子名称: CITRIC ACID, Polyubiquitin-C, Wc-VDT1, ...
著者Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K.
登録日2022-07-08
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins.
Nat Commun, 13, 2022
6EI1
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BU of 6ei1 by Molmil
Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA
分子名称: GLYCEROL, MALONATE ION, Polyubiquitin-B, ...
著者Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T.
登録日2017-09-16
公開日2018-03-07
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.732 Å)
主引用文献A family of unconventional deubiquitinases with modular chain specificity determinants.
Nat Commun, 9, 2018
5GOC
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BU of 5goc by Molmil
Lys11-linked diubiquitin
分子名称: D-ubiquitin, SODIUM ION, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.733 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
6FGE
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BU of 6fge by Molmil
Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin
分子名称: ACETATE ION, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Kwasna, D, Abdul Rehman, S.A, Kulathu, Y.
登録日2018-01-10
公開日2018-04-04
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.
Mol. Cell, 70, 2018
4MSM
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BU of 4msm by Molmil
Crystal structure of Schizosaccharomyces pombe AMSH-like protease sst2 E286A mutant bound to ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, PHOSPHATE ION, ...
著者Shrestha, R.K, Ronau, J.A, Das, C.
登録日2013-09-18
公開日2014-06-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
9AVW
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BU of 9avw by Molmil
Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin
分子名称: SULFATE ION, TGF-beta-activated kinase 1 and MAP3K7-binding protein 2, Ubiquitin, ...
著者Michel, M.A, Scutts, S, Komander, D.
登録日2024-03-05
公開日2024-07-31
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin
To be published
8ST8
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BU of 8st8 by Molmil
Structure of E3 ligase SopA bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8T2D
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BU of 8t2d by Molmil
Ubiquitin variant i53:Mutant T12Y.T14E.L67R with 53BP1 Tudor domain
分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53
著者Partridge, J.R, Holden, J.K, Wibowo, A.S, Mulichak, A.
登録日2023-06-05
公開日2024-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
4K7U
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BU of 4k7u by Molmil
Crystal structure of Zn2.3-hUb (human ubiquitin) adduct from a solution 70 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
4K7S
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BU of 4k7s by Molmil
Crystal structure of Zn2-hUb (human ubiquitin) adduct from a solution 35 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
4K7W
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BU of 4k7w by Molmil
Crystal structure of Zn3-hUb(human ubiquitin) adduct from a solution 100 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
6OI4
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BU of 6oi4 by Molmil
RPN13 (19-132)-RPN2 (940-952) pY950-Ub complex
分子名称: 1,2-ETHANEDIOL, 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, ...
著者Hemmis, C.W, Hill, C.P.
登録日2019-04-08
公開日2019-05-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Phosphorylation of Tyr-950 in the proteasome scaffolding protein RPN2 modulates its interaction with the ubiquitin receptor RPN13.
J.Biol.Chem., 294, 2019

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