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PDB: 549 件

6MSD
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BU of 6msd by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
8U5H
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BU of 8u5h by Molmil
Cryo-EM structure of human DNMT3A UDR bound to H2AK119ub1-modified nucleosome
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H2A, Histone H2B 1.1, ...
著者Chen, X, Song, J.
登録日2023-09-12
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
To Be Published
5UDH
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HHARI/ARIH1-UBCH7~Ubiquitin
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
著者Miller, D.J, Schulman, B.A.
登録日2016-12-27
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
6C16
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BU of 6c16 by Molmil
Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2018-01-04
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
4DDG
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BU of 4ddg by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
著者Juang, Y.C, Sanches, M, Sicheri, F.
登録日2012-01-18
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.2987 Å)
主引用文献OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
8C07
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Structure of HECT E3 UBR5 forming K48 linked Ubiquitin chains
分子名称: 5-azanylpentan-2-one, E3 ubiquitin-protein ligase UBR5, Polyubiquitin-B
著者Hehl, L.A, Prabu, J.R, Schulman, B.A.
登録日2022-12-16
公開日2023-08-23
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural snapshots along K48-linked ubiquitin chain formation by the HECT E3 UBR5.
Nat.Chem.Biol., 20, 2024
7DNJ
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BU of 7dnj by Molmil
K63-polyUb MDA5CARDs complex
分子名称: Interferon-induced helicase C domain-containing protein 1, Ubiquitin
著者Song, B, Chen, Y, Luo, D.H, Zheng, J.
登録日2020-12-09
公開日2021-10-13
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Immunity, 54, 2021
3JVZ
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BU of 3jvz by Molmil
E2~Ubiquitin-HECT
分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Souphron, J, Kamadurai, H.B, Schulman, B.A.
登録日2009-09-17
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex.
Mol.Cell, 36, 2009
6MSE
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BU of 6mse by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
7W3F
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BU of 7w3f by Molmil
Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y.
登録日2021-11-25
公開日2022-05-04
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
8J1P
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BU of 8j1p by Molmil
Cryo-EM structure of Ufd4 in complex with K29/48 triUb
分子名称: Ubiquitin, Ubiquitin fusion degradation protein 4
著者Ai, H.S, Mao, J.X, Wu, X.W, Pan, M, Liu, L.
登録日2023-04-13
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structural Insights into the Molecular Mechanism of Ufd4-catalyzed Elongation of K48-linked Ubiquitin Chain through Lys29 Linkage
To Be Published
5JTV
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BU of 5jtv by Molmil
USP7CD-UBL45 in complex with Ubiquitin
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.312 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
9AZJ
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BU of 9azj by Molmil
Structure of ubiquitinated NEMO UBAN K285C-Ub G76C bound to HOIP NZF1
分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Ubiquitin, ...
著者Michel, M.A, Scutts, S, Komander, D.
登録日2024-03-11
公開日2024-07-31
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin
To be published
8V25
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BU of 8v25 by Molmil
H2BK120ub-modified nucleosome ubiquitin position 1
分子名称: 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-11-21
公開日2024-08-28
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Nucleic Acids Res., 2024
5JTJ
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BU of 5jtj by Molmil
USP7CD-CTP in complex with Ubiquitin
分子名称: CALCIUM ION, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 7,Ubiquitin carboxyl-terminal hydrolase 7
著者Murray, J.M, Rouge, L.
登録日2016-05-09
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.321 Å)
主引用文献Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation.
Structure, 24, 2016
8V26
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BU of 8v26 by Molmil
H2BK120ub-modified nucleosome ubiquitin position 2
分子名称: 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-11-21
公開日2024-08-28
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Nucleic Acids Res., 2024
8V27
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BU of 8v27 by Molmil
H2BK120ub-modified nucleosome ubiquitin position 3
分子名称: 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-11-21
公開日2024-08-28
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Nucleic Acids Res., 2024
7MEX
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BU of 7mex by Molmil
Structure of yeast Ubr1 in complex with Ubc2 and N-degron
分子名称: E3 ubiquitin-protein ligase UBR1, N-degron, Ubiquitin, ...
著者Pan, M, Zheng, Q, Wang, T, Liang, L, Yu, Y, Liu, L, Zhao, M.
登録日2021-04-08
公開日2021-11-24
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural insights into Ubr1-mediated N-degron polyubiquitination.
Nature, 600, 2021
5CVN
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BU of 5cvn by Molmil
WDR48 (2-580):USP46~ubiquitin ternary complex
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
著者Harris, S.F, Yin, J.
登録日2015-07-27
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
8V28
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BU of 8v28 by Molmil
H2BK120ub-modified nucleosome ubiquitin position 4
分子名称: 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Hicks, C.W, Wolberger, C.
登録日2023-11-22
公開日2024-08-28
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch
Nucleic Acids Res., 2024
6VEN
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BU of 6ven by Molmil
Yeast COMPASS in complex with a ubiquitinated nucleosome
分子名称: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ...
著者Worden, E.J, Wolberger, C.
登録日2020-01-02
公開日2020-01-15
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome.
Elife, 9, 2020
7YQK
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BU of 7yqk by Molmil
cryo-EM structure of gammaH2AXK15ub-H4K20me2 nucleosome bound to 53BP1
分子名称: DNA (145-MER), Histone H2AX, Histone H2B, ...
著者Ai, H.S, GuoChao, C, Qingyue, G, Ze-Bin, T, Zhiheng, D, Xin, L, Fan, Y, Ziyu, X, Jia-Bin, L, Changlin, T, Liu, L.
登録日2022-08-07
公開日2022-08-17
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Chemical Synthesis of Post-Translationally Modified H2AX Reveals Redundancy in Interplay between Histone Phosphorylation, Ubiquitination, and Methylation on the Binding of 53BP1 with Nucleosomes.
J.Am.Chem.Soc., 144, 2022
8PJN
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BU of 8pjn by Molmil
Catalytic module of human CTLH E3 ligase bound to multiphosphorylated UBE2H~ubiquitin
分子名称: E3 ubiquitin-protein transferase MAEA, E3 ubiquitin-protein transferase RMND5A, Ubiquitin, ...
著者Chrustowicz, J, Sherpa, D, Prabu, R.J, Schulman, B.A.
登録日2023-06-23
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies.
Mol.Cell, 84, 2024
3OJ4
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BU of 3oj4 by Molmil
Crystal structure of the A20 ZnF4, ubiquitin and UbcH5A complex
分子名称: Tumor necrosis factor alpha-induced protein 3, Ubiquitin, Ubiquitin-conjugating enzyme E2 D1, ...
著者Bosanac, I, Hymowitz, S.G.
登録日2010-08-20
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Ubiquitin Binding to A20 ZnF4 Is Required for Modulation of NF-κB Signaling
Mol.Cell, 40, 2010
8OFF
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BU of 8off by Molmil
Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes (Map1)
分子名称: BRCA1 associated RING domain 1, DNA (142-MER), Histone H2A type 1, ...
著者Foglizzo, M, Burdett, H, Wilson, M.D, Zeqiraj, E.
登録日2023-03-15
公開日2023-10-11
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献BRCA1-BARD1 combines multiple chromatin recognition modules to bridge nascent nucleosomes.
Nucleic Acids Res., 51, 2023

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件を2024-09-11に公開中

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