5W0Z
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3IO4
| Huntingtin amino-terminal region with 17 Gln residues - Crystal C90 | 分子名称: | CALCIUM ION, Maltose-binding periplasmic protein,Huntingtin fusion protein, ZINC ION | 著者 | Kim, M.W, Chelliah, Y, Kim, S.W, Otwinowski, Z, Bezprozvanny, I. | 登録日 | 2009-08-13 | 公開日 | 2009-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | 主引用文献 | Secondary structure of Huntingtin amino-terminal region. Structure, 17, 2009
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8HLB
| Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2 | 分子名称: | TR109 heavy chain, TR109 light chain, TR92 heavy chain, ... | 著者 | Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K. | 登録日 | 2022-11-29 | 公開日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection. Commun Biol, 6, 2023
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8ZMS
| Acetylcholine-bound VAChT | 分子名称: | ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | 著者 | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | 登録日 | 2024-05-23 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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3IOV
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3IO6
| Huntingtin amino-terminal region with 17 Gln residues - crystal C92-a | 分子名称: | CALCIUM ION, Maltose-binding periplasmic protein, HUNTINGTIN FUSION PROTEIN, ... | 著者 | Kim, M.W, Chelliah, Y, Kim, S.W, Otwinowski, Z, Bezprozvanny, I. | 登録日 | 2009-08-13 | 公開日 | 2009-10-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Secondary structure of Huntingtin amino-terminal region. Structure, 17, 2009
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3IOU
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6HDA
| Crystal structure of the potassium channel MtTMEM175 with cesium | 分子名称: | CESIUM ION, DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, ... | 著者 | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis for ion selectivity in TMEM175 K+channels. Elife, 9, 2020
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5CL1
| Complex structure of Norrin with human Frizzled 4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-4, Maltose-binding periplasmic protein,Norrin | 著者 | Wang, Z, Ke, J, Shen, G, Cheng, Z, Xu, H.E, Xu, W. | 登録日 | 2015-07-16 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural basis of the Norrin-Frizzled 4 interaction. Cell Res., 25, 2015
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8G8W
| Molecular mechanism of nucleotide inhibition of human uncoupling protein 1 | 分子名称: | CARDIOLIPIN, GUANOSINE-5'-TRIPHOSPHATE, Mitochondrial brown fat uncoupling protein 1, ... | 著者 | Gogoi, P, Jones, S.A, Ruprecht, J.J, King, M.S, Lee, Y, Zogg, T, Pardon, E, Chand, D, Steimle, S, Copeman, D, Cotrim, C.A, Steyaert, J, Crichton, P.G, Moiseenkova-Bell, V, Kunji, E.R.S. | 登録日 | 2023-02-20 | 公開日 | 2023-06-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of purine nucleotide inhibition of human uncoupling protein 1. Sci Adv, 9, 2023
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8SOJ
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7Y5Q
| Structure of 1:1 PAPP-A.STC2 complex(half map) | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-06-17 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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7Z7H
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6DBU
| Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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8FNE
| phiPA3 PhuN Tetramer, p2 | 分子名称: | Maltose/maltodextrin-binding periplasmic protein, PhuN | 著者 | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | 登録日 | 2022-12-27 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice. Nat Commun, 14, 2023
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7P1H
| Structure of the V. vulnificus ExoY-G-actin-profilin complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Belyy, A, Merino, F, Raunser, S. | 登録日 | 2021-07-01 | 公開日 | 2021-11-17 | 最終更新日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens. Nat Commun, 12, 2021
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7JHH
| Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Fab and nanobody | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Yan, Y, Murkherjee, S, Zhou, X.E, Xu, T.H, Xu, H.E, Kossiakoff, A.A, Melcher, K. | 登録日 | 2020-07-20 | 公開日 | 2021-07-21 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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6BUZ
| Cryo-EM structure of CENP-A nucleosome in complex with kinetochore protein CENP-N | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | 著者 | Chittori, S, Hong, J, Kelly, A.E, Bai, Y, Subramaniam, S. | 登録日 | 2017-12-11 | 公開日 | 2017-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | 主引用文献 | Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N. Science, 359, 2018
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7M74
| ATP-bound AMP-activated protein kinase | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-2, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Yan, Y, Mukherjee, S, Harikumar, K.G, Strutzenberg, T, Zhou, X.E, Powell, S.K, Xu, T, Sheldon, R, Lamp, J, Brunzelle, J.S, Radziwon, K, Ellis, A, Novick, S.J, Vega, I.E, Jones, R, Miller, L.J, Xu, H.E, Griffin, P.R, Kossiakoff, A.A, Melcher, K. | 登録日 | 2021-03-26 | 公開日 | 2021-12-15 | 最終更新日 | 2021-12-22 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373, 2021
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7NZM
| Cryo-EM structure of pre-dephosphorylation complex of phosphorylated eIF2alpha with trapped holophosphatase (PP1A_D64A/PPP1R15A/G-actin/DNase I) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Yan, Y, Hardwick, S, Ron, D. | 登録日 | 2021-03-24 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Higher-order phosphatase-substrate contacts terminate the integrated stress response. Nat.Struct.Mol.Biol., 28, 2021
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6DBR
| Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | 分子名称: | CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6P6W
| Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | 分子名称: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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7VGQ
| Cryo-EM structure of Machupo virus polymerase L in complex with matrix protein Z | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,RING finger protein Z, RNA-directed RNA polymerase L, ZINC ION | 著者 | Zhang, X, Ma, J, Zhang, S. | 登録日 | 2021-09-18 | 公開日 | 2021-09-29 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of Machupo virus polymerase in complex with matrix protein Z. Nat Commun, 12, 2021
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8SOK
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8HGH
| Structure of 2:2 PAPP-A.STC2 complex | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | 登録日 | 2022-11-14 | 公開日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2. Cell Discov, 8, 2022
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