7M74
ATP-bound AMP-activated protein kinase
Summary for 7M74
Entry DOI | 10.2210/pdb7m74/pdb |
EMDB information | 23708 |
Related PRD ID | PRD_900001 |
Descriptor | 5'-AMP-activated protein kinase catalytic subunit alpha-1, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (12 entities in total) |
Functional Keywords | ampk, activation, atp-binding, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 7 |
Total formula weight | 216492.97 |
Authors | Yan, Y.,Mukherjee, S.,Harikumar, K.G.,Strutzenberg, T.,Zhou, X.E.,Powell, S.K.,Xu, T.,Sheldon, R.,Lamp, J.,Brunzelle, J.S.,Radziwon, K.,Ellis, A.,Novick, S.J.,Vega, I.E.,Jones, R.,Miller, L.J.,Xu, H.E.,Griffin, P.R.,Kossiakoff, A.A.,Melcher, K. (deposition date: 2021-03-26, release date: 2021-12-15, Last modification date: 2021-12-22) |
Primary citation | Yan, Y.,Mukherjee, S.,Harikumar, K.G.,Strutzenberg, T.S.,Zhou, X.E.,Suino-Powell, K.,Xu, T.H.,Sheldon, R.D.,Lamp, J.,Brunzelle, J.S.,Radziwon, K.,Ellis, A.,Novick, S.J.,Vega, I.E.,Jones, R.G.,Miller, L.J.,Xu, H.E.,Griffin, P.R.,Kossiakoff, A.A.,Melcher, K. Structure of an AMPK complex in an inactive, ATP-bound state. Science, 373:413-419, 2021 Cited by PubMed: 34437114DOI: 10.1126/science.abe7565 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.93 Å) |
Structure validation
Download full validation report