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PDB: 562 件

3RLF
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Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to MgAMPPNP
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, MAGNESIUM ION, Maltose transport system permease protein malF, ...
著者Oldham, M.L, Chen, J.
登録日2011-04-19
公開日2011-08-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Snapshots of the maltose transporter during ATP hydrolysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
1ZKB
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BU of 1zkb by Molmil
Zinc-free Engineered maltose binding protein
分子名称: Maltose-binding periplasmic protein
著者Telmer, P.G, Shilton, B.H.
登録日2005-05-02
公開日2005-12-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural studies of an engineered zinc biosensor reveal an unanticipated mode of zinc binding.
J.Mol.Biol., 354, 2005
6OB5
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BU of 6ob5 by Molmil
Computationally-designed, modular sense/response system (S3-2D)
分子名称: Ankyrin Repeat Domain (AR), S3-2D variant, FARNESYL DIPHOSPHATE, ...
著者Thompson, M.C, Glasgow, A.A, Huang, Y.M, Fraser, J.S, Kortemme, T.
登録日2019-03-19
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Computational design of a modular protein sense-response system.
Science, 366, 2019
4KYD
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BU of 4kyd by Molmil
Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP.
分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Maltose-binding periplasmic protein, Phosphoprotein, ...
著者Yegambaram, K, Bulloch, E.M.M, Kingston, R.L.
登録日2013-05-28
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Protein domain definition should allow for conditional disorder.
Protein Sci., 22, 2013
6D66
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BU of 6d66 by Molmil
Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16
分子名称: 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ...
著者Gumpena, R, Waugh, D.S, Lountos, G.T.
登録日2018-04-20
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.226 Å)
主引用文献MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
4OGM
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MBP-fusion protein of PilA1 residues 26-159
分子名称: Maltose ABC transporter periplasmic protein, pilin protein chimera, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Piepenbrink, K.H, Sundberg, E.J.
登録日2014-01-16
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.234 Å)
主引用文献Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile.
Structure, 23, 2015
5MES
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BU of 5mes by Molmil
MCL1 FAB COMPLEX IN COMPLEX WITH COMPOUND 29
分子名称: (5~{R},13~{S},17~{S})-5-[[4-chloranyl-3-(2-phenylethyl)phenyl]methyl]-13-[(4-chlorophenyl)methyl]-8-methyl-1,4,8,12,16-pentazatricyclo[15.8.1.0^{20,25}]hexacosa-20(25),21,23-triene-3,7,15,26-tetrone, Heavy Chain, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1, ...
著者Hargreaves, D.
登録日2016-11-16
公開日2017-01-18
最終更新日2017-03-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett, 8, 2017
6QB6
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Mcl1 in complex with a Fab
分子名称: Fab Heavy Chain, Fab Light Chain, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Hargreaves, D.
登録日2018-12-20
公開日2019-11-06
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Acta Crystallogr D Struct Biol, 75, 2019
1SVX
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BU of 1svx by Molmil
Crystal structure of a designed selected Ankyrin Repeat protein in complex with the Maltose Binding Protein
分子名称: Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
著者Binz, H.K, Amstutz, P, Kohl, A, Stumpp, M.T, Briand, C, Forrer, P, Gruetter, M.G, Plueckthun, A.
登録日2004-03-30
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
5GXT
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BU of 5gxt by Molmil
Crystal structure of PigG
分子名称: MAGNESIUM ION, Maltose-binding periplasmic protein,PigG
著者Zhang, F, Ran, T, Xu, D, Wang, W.
登録日2016-09-20
公開日2017-07-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.245 Å)
主引用文献Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14.
Int. J. Biol. Macromol., 99, 2017
4XR8
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BU of 4xr8 by Molmil
Crystal structure of the HPV16 E6/E6AP/p53 ternary complex at 2.25 A resolution
分子名称: 1,2-ETHANEDIOL, Cellular tumor antigen p53, DI(HYDROXYETHYL)ETHER, ...
著者Martinez-Zapien, D, Ruiz, F.X, Mitschler, A, Podjarny, A, Trave, G, Zanier, K.
登録日2015-01-20
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Nature, 529, 2016
4WTH
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BU of 4wth by Molmil
Ataxin-3 Carboxy Terminal Region - Crystal C2 (triclinic)
分子名称: Maltose-binding periplasmic protein, Ataxin-3 chimera, ZINC ION, ...
著者Zhemkov, V.A, Kim, M.
登録日2014-10-30
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The 2.2-Angstrom resolution crystal structure of the carboxy-terminal region of ataxin-3.
FEBS Open Bio, 6, 2016
6MBE
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BU of 6mbe by Molmil
Human Mcl-1 in complex with the designed peptide dM7
分子名称: CHLORIDE ION, Induced myeloid leukemia cell differentiation protein Mcl-1, dM7
著者Jenson, J.M, Keating, A.E.
登録日2018-08-29
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Tertiary Structural Motif Sequence Statistics Enable Facile Prediction and Design of Peptides that Bind Anti-apoptotic Bfl-1 and Mcl-1.
Structure, 27, 2019
6FS0
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BU of 6fs0 by Molmil
INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN FABCOMPLEX IN COMPLEX WITH AZD5991
分子名称: AZD5991, Fab Heavy Chain, Fab Light Chain, ...
著者Hargreaves, D.
登録日2018-02-18
公開日2018-12-26
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Nat Commun, 9, 2018
3HST
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BU of 3hst by Molmil
N-Terminal RNASE H domain of rv2228c from mycobacterium tuberculosis as a fusion protein with maltose binding protein
分子名称: 1,2-ETHANEDIOL, D(-)-TARTARIC ACID, Maltose-binding periplasmic protein, ...
著者Watkins, H.A, Baker, E.N.
登録日2009-06-10
公開日2010-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and functional characterization of an RNase HI domain from the bifunctional protein Rv2228c from Mycobacterium tuberculosis.
J.Bacteriol., 192, 2010
6B4L
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BU of 6b4l by Molmil
Crystal structure of MCL-1 in complex with a BIM competitive inhibitor
分子名称: 3-{3-[(naphthalen-1-yl)oxy]propyl}-1H-indole-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Judge, R.A, Souers, A.J.
登録日2017-09-26
公開日2017-10-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity.
J. Med. Chem., 58, 2015
7DDE
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BU of 7dde by Molmil
Cryo-EM structure of the Ape4 and Nbr1 complex
分子名称: Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION
著者Zhang, J, Ye, K.
登録日2020-10-28
公開日2021-07-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1.
Embo J., 40, 2021
4JKM
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BU of 4jkm by Molmil
Crystal Structure of Clostridium perfringens beta-glucuronidase
分子名称: Beta-glucuronidase, Maltose-binding periplasmic protein
著者Wallace, B.D, Redinbo, M.R.
登録日2013-03-09
公開日2014-09-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.263 Å)
主引用文献Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
6ANV
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BU of 6anv by Molmil
Crystal structure of anti-CRISPR protein AcrF1
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Yang, H, Patel, D.J.
登録日2017-08-14
公開日2017-10-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.265 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6NDJ
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BU of 6ndj by Molmil
Crystal structure of human NLRP6 PYD domain with MBP fusion
分子名称: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera
著者Shen, C, Fu, T.M, Wu, H.
登録日2018-12-13
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6SQC
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BU of 6sqc by Molmil
Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR containing alpha-methylated Leu1055 and Leu1076
分子名称: 1,2-ETHANEDIOL, Maltose/maltodextrin-binding periplasmic protein,CREB-binding protein, Nuclear receptor coactivator 3, ...
著者Bauer, V, Schmidtgall, B, Gogl, G, Dolenc, j, Osz, J, Kostmann, C, Mitschler, A, Cousido-Siah, A, Rochel, N, Trave, G, Kieffer, B, Torbeev, V.
登録日2019-09-03
公開日2020-09-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Conformational editing of intrinsically disordered protein by alpha-methylation.
Chem Sci, 12, 2020
3PY7
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Crystal structure of full-length Bovine Papillomavirus oncoprotein E6 in complex with LD1 motif of paxillin at 2.3A resolution
分子名称: ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose-binding periplasmic protein,paxillin LD1,protein E6 chimera
著者Cavarelli, J.
登録日2010-12-12
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.288 Å)
主引用文献Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
Science, 339, 2013
4DXB
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BU of 4dxb by Molmil
2.29A structure of the engineered MBP TEM-1 fusion protein RG13 in complex with zinc, P1 space group
分子名称: Maltose-binding periplasmic protein, Beta-lactamase TEM chimera, ZINC ION
著者van den Akker, F, Ke, W.
登録日2012-02-27
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of an Engineered beta-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric Regulation.
Plos One, 7, 2012
6EQZ
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A MamC-MIC insertion in MBP scaffold at position K170
分子名称: Maltose-binding periplasmic protein,Tightly bound bacterial magnetic particle protein,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Nudelman, H, Zarivach, R.
登録日2017-10-16
公開日2017-11-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献The importance of the helical structure of a MamC-derived magnetite-interacting peptide for its function in magnetite formation.
Acta Crystallogr D Struct Biol, 74, 2018
5CBN
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Fusion protein of mbp3-16 and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS
分子名称: 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid}, Maltose-binding periplasmic protein, mbp3-16,Immunoglobulin G-binding protein A
著者Jeong, W.H, Lee, H, Song, D.H, Lee, J.O.
登録日2015-07-01
公開日2016-03-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker.
Nat Commun, 7, 2016

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