6ANV

Crystal structure of anti-CRISPR protein AcrF1

Summary for 6ANV

Entry DOI	10.2210/pdb6anv/pdb
Related PRD ID	PRD_900010
Descriptor	anti-CRISPR protein AcrF1 fused with C-terminal MBP tag, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (7 entities in total)
Functional Keywords	type i-f crispr-cas system: csy cascade: structure: anti-crispr protein: inhibition of csy complex: genome editing tool, immune system
Biological source	Pseudomonas phage JBD30 More
Total number of polymer chains	2
Total formula weight	102897.75
Authors	Yang, H.,Patel, D.J. (deposition date: 2017-08-14, release date: 2017-10-25, Last modification date: 2023-10-04)
Primary citation	Guo, T.W.,Bartesaghi, A.,Yang, H.,Falconieri, V.,Rao, P.,Merk, A.,Eng, E.T.,Raczkowski, A.M.,Fox, T.,Earl, L.A.,Patel, D.J.,Subramaniam, S. Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell, 171:414-426.e12, 2017 Cited by PubMed: 28985564 DOI: 10.1016/j.cell.2017.09.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.265 Å)

Structure validation