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PDB: 22 件
2PBD
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BU of 2pbd by Molmil
Ternary complex of profilin-actin with the poly-PRO-GAB domain of VASP*
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Ferron, F, Rebowski, G, Dominguez, R.
登録日2007-03-28
公開日2007-11-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP
Embo J., 26, 2007
8BJH
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BU of 8bjh by Molmil
chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
著者Teixeira-Nunes, M, Renault, L, Retailleau, P.
登録日2022-11-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
8BJJ
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BU of 8bjj by Molmil
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, bound to ATP-Mg-actin, human profilin 1 and a sulfate ion
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Teixeira-Nunes, M, Renault, L, Retailleau, P.
登録日2022-11-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
8BJI
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BU of 8bji by Molmil
chimera of ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo fused to a proline-Rich-Domain (PRD) and profilin, bound to ADP-Mg-actin and a sulfate ion
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
著者Teixeira-Nunes, M, Renault, L, Retailleau, P.
登録日2022-11-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
2PAV
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BU of 2pav by Molmil
Ternary complex of Profilin-Actin with the Last Poly-Pro of Human VASP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Ferron, F, Rebowski, G, Dominguez, R.
登録日2007-03-27
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.
Embo J., 26, 2007
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-07
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
1FIL
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BU of 1fil by Molmil
HUMAN PLATELET PROFILIN I CRYSTALLIZED IN HIGH SALT ACTIN-BINDING PROTEIN
分子名称: PROFILIN, SULFATE ION
著者Fedorov, A.A, Pollard, T.D, Almo, S.C.
登録日1996-04-29
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Profilin at 2.0 Angstroms Resolution
To be Published
4X1L
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BU of 4x1l by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
分子名称: PHOSPHATE ION, Profilin-1
著者Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
登録日2014-11-24
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X1M
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BU of 4x1m by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
分子名称: Profilin-1
著者Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
登録日2014-11-24
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
1AWI
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BU of 1awi by Molmil
HUMAN PLATELET PROFILIN COMPLEXED WITH THE L-PRO10 PEPTIDE
分子名称: L-PRO10, PROFILIN
著者Mahoney, N.M, Almo, S.C.
登録日1997-10-02
公開日1998-10-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the profilin-poly-L-proline complex involved in morphogenesis and cytoskeletal regulation.
Nat.Struct.Biol., 4, 1997
1CF0
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BU of 1cf0 by Molmil
HUMAN PLATELET PROFILIN COMPLEXED WITH AN L-PRO10-IODOTYROSINE PEPTIDE
分子名称: PROTEIN (L-PRO10-IODOTYROSINE), PROTEIN (PROFILIN)
著者Rozwarski, D.A, Mahoney, N.M, Almo, S.C.
登録日1999-03-23
公開日1999-07-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Profilin binds proline-rich ligands in two distinct amide backbone orientations.
Nat.Struct.Biol., 6, 1999
8BR0
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BU of 8br0 by Molmil
ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin
分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
著者Texeira-Nuns, M, Retailleau, P, Renault, L.
登録日2022-11-22
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.218 Å)
主引用文献Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
4X25
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BU of 4x25 by Molmil
Structural basis for mutation-induced destabilization of Profilin 1 in ALS
分子名称: Profilin-1
著者Silvas, T.V, Shandilya, S.M.D, Schiffer, C.A.
登録日2014-11-25
公開日2015-06-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural basis for mutation-induced destabilization of profilin 1 in ALS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
3CHW
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BU of 3chw by Molmil
Complex of Dictyostelium discoideum Actin with Profilin and the Last Poly-Pro of Human VASP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Major actin, ...
著者Baek, K, Dominguez, R.
登録日2008-03-10
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1CJF
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BU of 1cjf by Molmil
PROFILIN BINDS PROLINE-RICH LIGANDS IN TWO DISTINCT AMIDE BACKBONE ORIENTATIONS
分子名称: 7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN, PROTEIN (HUMAN PLATELET PROFILIN), PROTEIN (PROLINE PEPTIDE)
著者Mahoney, N.M, Fedorov, A.A, Fedorov, E, Rozwarski, D.A, Almo, S.C.
登録日1999-04-13
公開日1999-07-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Profilin binds proline-rich ligands in two distinct amide backbone orientations.
Nat.Struct.Biol., 6, 1999
1FIK
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BU of 1fik by Molmil
HUMAN PLATELET PROFILIN I CRYSTALLIZED IN LOW SALT
分子名称: PHOSPHATE ION, PROFILIN
著者Fedorov, A.A, Pollard, T.D, Almo, S.C.
登録日1996-04-29
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Profilin at 2.0 Angstroms Resolution
To be Published
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-10
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Rebowski, G, Boczkowska, M, Dominguez, R.
登録日2018-12-06
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
9AZP
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BU of 9azp by Molmil
INF2 at the Barbed End of F-Actin with Incoming Profilin-Actin
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Palmer, N.J, Barrie, K.R, Dominguez, R.
登録日2024-03-11
公開日2024-05-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Mechanisms of actin filament severing and elongation by formins.
Nature, 2024
7P1H
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BU of 7p1h by Molmil
Structure of the V. vulnificus ExoY-G-actin-profilin complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Belyy, A, Merino, F, Raunser, S.
登録日2021-07-01
公開日2021-11-17
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.
Nat Commun, 12, 2021
8RTY
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BU of 8rty by Molmil
Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P.
登録日2024-01-29
公開日2024-04-10
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (6.25 Å)
主引用文献Molecular mechanism of actin filament elongation by formins.
Science, 384, 2024
1PFL
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BU of 1pfl by Molmil
REFINED SOLUTION STRUCTURE OF HUMAN PROFILIN I
分子名称: PROFILIN I
著者Metzler, W.J, Farmer II, B.T, Constantine, K.L, Friedrichs, M.S, Lavoie, T, Mueller, L.
登録日1994-12-12
公開日1995-03-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Refined solution structure of human profilin I.
Protein Sci., 4, 1995

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件を2024-07-31に公開中

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