3CHW

Complex of Dictyostelium discoideum Actin with Profilin and the Last Poly-Pro of Human VASP

Summary for 3CHW

Entry DOI	10.2210/pdb3chw/pdb
Related	2CI5 2CIP 2PAV
Descriptor	Major actin, Profilin-1, Vasodilator-stimulated phosphoprotein 16-residue peptide, ... (6 entities in total)
Functional Keywords	ternary complex, profilin, actin, dictyostelium discoideum, vasp, poly-proline, methyl histidine, atp-binding, cytoskeleton, nucleotide-binding, phosphoprotein, structural protein, actin-binding, cell junction, cell projection, membrane, sh3-binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm, cytoskeleton: P07830 P07737 Cytoplasm: P50552
Total number of polymer chains	3
Total formula weight	58502.21
Authors	Baek, K.,Dominguez, R. (deposition date: 2008-03-10, release date: 2008-08-19, Last modification date: 2023-08-30)
Primary citation	Baek, K.,Liu, X.,Ferron, F.,Shu, S.,Korn, E.D.,Dominguez, R. Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding. Proc.Natl.Acad.Sci.Usa, 105:11748-11753, 2008 Cited by PubMed: 18689676 DOI: 10.1073/pnas.0805852105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation