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PDB: 17 件
5MEO
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BU of 5meo by Molmil
Human Leukocyte Antigen presenting ILGKFLHRL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.772 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MER
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BU of 5mer by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHEL
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5MEQ
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BU of 5meq by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHTL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
5UGW
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BU of 5ugw by Molmil
STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN
分子名称: GLUTATHIONE, Telomerase reverse transcriptase
著者Skordalakes, E, Hoffman, H.
登録日2017-01-10
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes.
J. Biol. Chem., 292, 2017
4B18
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BU of 4b18 by Molmil
The crystal structure of human Importin alpha 5 with TERT NLS peptide
分子名称: IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE
著者Kim, K.L, Yoo, J.H, Cho, H.S.
登録日2012-07-08
公開日2013-09-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation.
J.Cell.Sci., 128, 2015
5MEP
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BU of 5mep by Molmil
Human Leukocyte Antigen A02 presenting ILGKFLHWL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K, Lloyd, A, Crowther, M, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
4MNQ
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BU of 4mnq by Molmil
TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Jakobsen, B.K.
登録日2013-09-11
公開日2013-11-13
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.742 Å)
主引用文献T-cell receptor (TCR)-peptide specificity overrides affinity-enhancing TCR-major histocompatibility complex interactions.
J.Biol.Chem., 289, 2014
2BCK
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BU of 2bck by Molmil
Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Rizkallah, P.J, Jakobsen, B.K, Cole, D.K, Gao, G.F.
登録日2005-10-19
公開日2006-01-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of HLA-A*2402 complexed with a telomerase peptide.
Eur.J.Immunol., 36, 2006
5MEN
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BU of 5men by Molmil
Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K.
登録日2016-11-16
公開日2016-12-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase.
J. Biol. Chem., 292, 2017
7QXA
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BU of 7qxa by Molmil
Cryo-EM map of human telomerase-DNA-TPP1 complex (sharpened)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7TRD
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BU of 7trd by Molmil
Human telomerase catalytic core structure at 3.3 Angstrom
分子名称: Telomerase RNA, partial sequence, Telomerase reverse transcriptase, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7TRE
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BU of 7tre by Molmil
Human telomerase catalytic core with shelterin protein TPP1
分子名称: Adrenocortical dysplasia protein homolog, Telomerase RNA, partial sequence, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7V99
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BU of 7v99 by Molmil
catalytic core of human telomerase holoenzyme
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ...
著者Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
登録日2021-08-24
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
7TRF
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BU of 7trf by Molmil
Human telomerase catalytic core RNP with H2A/H2B
分子名称: Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ...
著者Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J.
登録日2022-01-28
公開日2022-04-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
7BG9
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BU of 7bg9 by Molmil
The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate
分子名称: DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ...
著者Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K.
登録日2021-01-06
公開日2021-04-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of human telomerase holoenzyme with bound telomeric DNA.
Nature, 593, 2021
7QXS
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BU of 7qxs by Molmil
Cryo-EM structure of human telomerase-DNA-TPP1-POT1 complex (with POT1 side chains)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-27
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022
7QXB
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BU of 7qxb by Molmil
Cryo-EM map of human telomerase-DNA-TPP1-POT1 complex (sharpened map)
分子名称: Adrenocortical dysplasia homolog (Mouse), isoform CRA_a, Histone H2A, ...
著者Sekne, Z, Ghanim, G.E, van Roon, A.M.M, Nguyen, T.H.D.
登録日2022-01-26
公開日2022-03-02
最終更新日2022-03-23
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Structural basis of human telomerase recruitment by TPP1-POT1.
Science, 375, 2022

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件を2024-09-11に公開中

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