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PDB: 8 件

6UMX
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BU of 6umx by Molmil
Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015
分子名称: GL29H4-16 Fab Heavy Chain,GL29H4-16 Fab Heavy Chain, GL29H4-16 Fab Light Chain,GL29H4-16 Fab Light Chain, GLYCEROL, ...
著者Dagbay, K.B, Treece, E, Streich Jr, F.C, Jackson, J.W, Faucette, R.R, Nikiforov, A, Lin, S.C, Bostion, C.J, Nicholls, S.B, Capili, A.D, Carven, G.J.
登録日2019-10-10
公開日2020-02-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015.
J.Biol.Chem., 295, 2020
3HH2
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BU of 3hh2 by Molmil
Crystal structure of the myostatin:follistatin 288 complex
分子名称: CITRIC ACID, Follistatin, Growth/differentiation factor 8, ...
著者Cash, J.N, Thompson, T.B.
登録日2009-05-14
公開日2009-08-04
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
Embo J., 28, 2009
5JI1
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BU of 5ji1 by Molmil
Crystal Structure of GDF8
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Growth/differentiation factor 8
著者Walker, R.G, Thompson, T.B.
登録日2016-04-21
公開日2017-03-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
3SEK
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BU of 3sek by Molmil
Crystal Structure of the Myostatin:Follistatin-like 3 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8
著者Cash, J.N, Thompson, T.B.
登録日2011-06-10
公開日2011-11-02
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
5NTU
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BU of 5ntu by Molmil
Crystal Structure of human Pro-myostatin Precursor at 2.6 A Resolution
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Growth/differentiation factor 8
著者Cotton, T.R, Fischer, G, Hyvonen, M.
登録日2017-04-28
公開日2018-01-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure of the human myostatin precursor and determinants of growth factor latency.
EMBO J., 37, 2018
5NXS
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BU of 5nxs by Molmil
Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling
分子名称: Growth/differentiation factor 8
著者Cotton, T.R, Fischer, G, Hyvonen, M.
登録日2017-05-10
公開日2018-01-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (4.19 Å)
主引用文献Structure of the human myostatin precursor and determinants of growth factor latency.
EMBO J., 37, 2018
5F3H
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BU of 5f3h by Molmil
Structure of myostatin in complex with humanized RK35 antibody
分子名称: Growth/differentiation factor 8, humanized RK35 antibody heavy chain, humanized RK35 antibody light chain
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016
5F3B
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BU of 5f3b by Molmil
Structure of myostatin in complex with chimeric RK35 antibody
分子名称: GLYCEROL, Growth/differentiation factor 8, RK35 Chimeric antibody heavy chain, ...
著者Parris, K.D, Mosyak, L.
登録日2015-12-02
公開日2016-09-28
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody.
Mabs, 8, 2016

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件を2025-04-30に公開中

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