3HH2

Crystal structure of the myostatin:follistatin 288 complex

Summary for 3HH2

Entry DOI	10.2210/pdb3hh2/pdb
Descriptor	Growth/differentiation factor 8, Follistatin, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	protein-protein complex, tb domain, cystine knot motif, tgf-beta fold, disulfide linked dimer, follistatin domain (fsd), cleavage on pair of basic residues, cytokine, disulfide bond, glycoprotein, growth factor, secreted, signaling protein-cytokine complex, signaling protein/cytokine
Biological source	Mus musculus (mouse) More
Cellular location	Secreted : O08689 P19883
Total number of polymer chains	4
Total formula weight	88698.00
Authors	Cash, J.N.,Thompson, T.B. (deposition date: 2009-05-14, release date: 2009-08-04, Last modification date: 2017-11-01)
Primary citation	Cash, J.N.,Rejon, C.A.,McPherron, A.C.,Bernard, D.J.,Thompson, T.B. The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding Embo J., 28:2662-2676, 2009 Cited by PubMed: 19644449 DOI: 10.1038/emboj.2009.205 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation