5NXS
Crystal Structure of Human Pro-myostatin Precursor at 4.2 A Resolution with Experimental Phases from SeMet labelling
Summary for 5NXS
| Entry DOI | 10.2210/pdb5nxs/pdb |
| Descriptor | Growth/differentiation factor 8 (1 entity in total) |
| Functional Keywords | growth factor, signaling protein, tgfbeta family, cystine knot |
| Biological source | Homo sapiens (Human) |
| Cellular location | Secreted : O14793 |
| Total number of polymer chains | 2 |
| Total formula weight | 76995.85 |
| Authors | Cotton, T.R.,Fischer, G.,Hyvonen, M. (deposition date: 2017-05-10, release date: 2018-01-17, Last modification date: 2018-02-21) |
| Primary citation | Cotton, T.R.,Fischer, G.,Wang, X.,McCoy, J.C.,Czepnik, M.,Thompson, T.B.,Hyvonen, M. Structure of the human myostatin precursor and determinants of growth factor latency. EMBO J., 37:367-383, 2018 Cited by PubMed: 29330193DOI: 10.15252/embj.201797883 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.19 Å) |
Structure validation
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