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PDB: 280 件

4KGC
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BU of 4kgc by Molmil
Nucleosome Core Particle Containing (ETA6-P-CYMENE)-(1, 2-ETHYLENEDIAMINE)-RUTHENIUM
分子名称: (ethane-1,2-diamine-kappa~2~N,N')[(1,2,3,4,5,6-eta)-1-methyl-4-(propan-2-yl)cyclohexane-1,2,3,4,5,6-hexayl]ruthenium, DNA (145-mer), Histone H2A, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-04-29
公開日2014-03-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Ligand substitutions between ruthenium-cymene compounds can control protein versus DNA targeting and anticancer activity
Nat Commun, 5, 2014
1P34
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BU of 1p34 by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
2IO5
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BU of 2io5 by Molmil
Crystal structure of the CIA- histone H3-H4 complex
分子名称: ASF1A protein, Histone H3.1, Histone H4
著者Natsume, R, Akai, Y, Horikoshi, M, Senda, T.
登録日2006-10-10
公開日2007-02-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.
Nature, 446, 2007
3REL
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BU of 3rel by Molmil
2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride
分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2011-04-04
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
1P3P
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BU of 1p3p by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
1P3G
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BU of 1p3g by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
8CWW
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BU of 8cww by Molmil
Structure of S. cerevisiae Hop1 CBR bound to a nucleosome
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Gu, Y, Ur, S.N, Milano, C.R, Tromer, E.C, Vale-Silva, L.A, Hochwagen, A, Corbett, K.D.
登録日2022-05-19
公開日2023-06-07
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Chromatin binding by HORMAD proteins regulates meiotic recombination initiation.
Embo J., 43, 2024
1P3O
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BU of 1p3o by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
登録日2003-04-17
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
3LJA
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BU of 3lja by Molmil
Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome
分子名称: 147mer DNA, Histone H2A, Histone H2B 1.1, ...
著者Wu, B, Davey, C.A.
登録日2010-01-26
公開日2010-04-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Using soft X-rays for a detailed picture of divalent metal binding in the nucleosome
J.Mol.Biol., 398, 2010
5ONG
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BU of 5ong by Molmil
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Barth, P.D, Richmond, T.J.
登録日2017-08-03
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
7YI1
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BU of 7yi1 by Molmil
Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome
分子名称: Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ...
著者Li, H.T, Yan, C.Y, Guan, H.P, Wang, P.
登録日2022-07-14
公開日2023-06-14
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
Nature, 620, 2023
5DNN
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BU of 5dnn by Molmil
Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Ma, Z, Davey, C.A.
登録日2015-09-10
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
5ONW
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BU of 5onw by Molmil
X-Ray crystal structure of a nucleosome core particle with its DNA site-specifically crosslinked to the histone octamer and the two H2A/H2B dimers crosslinked via H2A N38C
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Barth, P.D, Richmond, T.J.
登録日2017-08-04
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
8TOF
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BU of 8tof by Molmil
Rpd3S bound to an H3K36Cme3 modified nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ...
著者Markert, J.W, Vos, S.M, Farnung, L.
登録日2023-08-03
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
7VDT
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BU of 7vdt by Molmil
The motor-nucleosome module of human chromatin remodeling PBAF-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (207-MER), ...
著者Chen, Z.C, Chen, K.J, Yuan, J.J.
登録日2021-09-07
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
1AOI
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BU of 1aoi by Molmil
COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT
分子名称: HISTONE H2A, HISTONE H2B, HISTONE H3, ...
著者Luger, K, Maeder, A.W, Richmond, R.K, Sargent, D.F, Richmond, T.J.
登録日1997-07-03
公開日1998-09-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the nucleosome core particle at 2.8 A resolution.
Nature, 389, 1997
5MLU
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BU of 5mlu by Molmil
Crystal structure of the PFV GAG CBS bound to a mononucleosome
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B, ...
著者Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P.
登録日2016-12-07
公開日2017-05-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for spumavirus GAG tethering to chromatin.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8V6V
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BU of 8v6v by Molmil
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-12-03
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8V4Y
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BU of 8v4y by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-11-29
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
6WZ9
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BU of 6wz9 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
分子名称: DNA, Histone H2A, Histone H2B 1.1, ...
著者Halic, M, Bilokapic, S.
登録日2020-05-13
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
7XFN
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BU of 7xfn by Molmil
Structure of nucleosome-DI complex (-55I, Apo state)
分子名称: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Zheng, L, Tsai, B, Gao, N.
登録日2022-04-01
公開日2023-04-19
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7XFL
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BU of 7xfl by Molmil
Structure of nucleosome-AAG complex (A-53I, free state)
分子名称: DNA (152-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Zheng, L, Tsai, B, Gao, N.
登録日2022-04-01
公開日2023-04-19
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural and mechanistic insights into the DNA glycosylase AAG-mediated base excision in nucleosome.
Cell Discov, 9, 2023
7ENN
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BU of 7enn by Molmil
The structure of ALC1 bound to the nucleosome
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ...
著者Chen, Z.C, Chen, K.J, Wang, L.
登録日2021-04-18
公開日2021-07-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
5E5A
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BU of 5e5a by Molmil
Crystal structure of the chromatin-tethering domain of Human cytomegalovirus IE1 protein bound to the nucleosome core particle
分子名称: C-terminal domain of Regulatory protein IE1, DNA (146-MER), Histone H2A, ...
著者Fang, Q, Chen, P, Wang, M, Fang, J, Yang, N, Li, G, Xu, R.M.
登録日2015-10-08
公開日2016-02-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Human cytomegalovirus IE1 protein alters the higher-order chromatin structure by targeting the acidic patch of the nucleosome
Elife, 5, 2016
5DNM
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BU of 5dnm by Molmil
Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Muhammad, R, Davey, C.A.
登録日2015-09-10
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017

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