3REL

2.7 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b) Derivatized with Triamminechloroplatinum(II) Chloride

Summary for 3REL

Related1KX3 1KX4 1KX5 2NZD 3REH 3REI 3REJ 3REK
DescriptorHistone H3.2, Histone H4, Histone H2A, ... (8 entities in total)
Functional Keywordsnucleosome, structural protein-dna complex, structural protein/dna
Biological sourceXenopus laevis (clawed frog,common platanna,platanna)
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Cellular locationNucleus P84233 P62799 P06897 P02281
Total number of polymer chains10
Total molecular weight208011.8
Authors
Wu, B.,Davey, C.A. (deposition date: 2011-04-04, release date: 2012-03-14)
Primary citation
Wu, B.,Davey, G.E.,Nazarov, A.A.,Dyson, P.J.,Davey, C.A.
Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39:8200-8212, 2011
PubMed: 21724603 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkr491
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.30160.8%7.0%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution