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PDB: 11 件

7ZGO
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BU of 7zgo by Molmil
Cryo-EM structure of human NKCC1 (TM domain)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ...
著者Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J.
登録日2022-04-04
公開日2022-10-05
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Embo J., 41, 2022
7S1X
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BU of 7s1x by Molmil
Cryo-EM structure of human NKCC1 K289NA492EL671C bound with bumetanide
分子名称: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, CHLORIDE ION, POTASSIUM ION, ...
著者Zhao, Y.X, Cao, E.H.
登録日2021-09-02
公開日2022-05-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Nat Commun, 13, 2022
7SMP
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CryoEM structure of NKCC1 Bu-I
分子名称: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, POTASSIUM ION, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2021-10-26
公開日2022-09-28
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
7S1Z
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BU of 7s1z by Molmil
Cryo-EM structure of Human NKCC1 K289NA492EL671C
分子名称: Solute carrier family 12 member 2
著者Zhao, Y.X, Cao, E.H.
登録日2021-09-02
公開日2022-05-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Nat Commun, 13, 2022
7N3N
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BU of 7n3n by Molmil
CryoEM structure of human NKCC1 state Fu-I
分子名称: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2021-06-01
公開日2022-09-28
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
8STE
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BU of 8ste by Molmil
Cryo-EM structure of NKCC1 Fu_CTD
分子名称: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2023-05-10
公開日2023-05-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
6PZT
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BU of 6pzt by Molmil
cryo-EM structure of human NKCC1
分子名称: Solute carrier family 12 member 2
著者Cao, E, Wang, Q, Yang, X.
登録日2019-08-01
公開日2020-03-25
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structure of the human cation-chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy.
Nat Commun, 11, 2020
7MXO
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BU of 7mxo by Molmil
CryoEM structure of human NKCC1
分子名称: CHLORIDE ION, POTASSIUM ION, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2021-05-19
公開日2022-09-28
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022
7D10
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BU of 7d10 by Molmil
Human NKCC1
分子名称: PALMITIC ACID, Solute carrier family 12 member 2
著者Zhang, S, Yang, M.
登録日2020-09-12
公開日2021-04-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
7S1Y
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BU of 7s1y by Molmil
Cryo-EM structure of human NKCC1 K289NA492E bound with bumetanide
分子名称: 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid, CHLORIDE ION, POTASSIUM ION, ...
著者Zhao, Y.X, Cao, E.h.
登録日2021-09-02
公開日2022-05-25
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for inhibition of the Cation-chloride cotransporter NKCC1 by the diuretic drug bumetanide
Nat Commun, 13, 2022
7SFL
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BU of 7sfl by Molmil
Human NKCC1 state Fu-II
分子名称: 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID, Solute carrier family 12 member 2
著者Moseng, M.A.
登録日2021-10-04
公開日2022-09-28
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling.
Sci Adv, 8, 2022

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件を2024-07-10に公開中

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