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PDB: 461 件

2B2U
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BU of 2b2u by Molmil
Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2
分子名称: Chromodomain-helicase-DNA-binding protein 1, Histone H3
著者Flanagan IV, J.F, Mi, L.-Z, Chruszcz, M, Cymborowski, M, Clines, K.L, Kim, Y, Minor, W, Rastinejad, F, Khorasanizadeh, S.
登録日2005-09-19
公開日2005-12-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Double chromodomains cooperate to recognize the methylated histone H3 tail.
Nature, 438, 2005
4Z2M
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BU of 4z2m by Molmil
Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex
分子名称: FACT complex subunit SPT16, Histone H3.1, Histone H4
著者Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K.
登録日2015-03-30
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.981 Å)
主引用文献Integrated molecular mechanism directing nucleosome reorganization by human FACT.
Genes Dev., 30, 2016
3B95
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BU of 3b95 by Molmil
EuHMT1 (Glp) Ankyrin Repeat Domain (Structure 2)
分子名称: Euchromatic histone-lysine N-methyltransferase 1, Histone H3 N-terminal Peptide, SULFATE ION
著者Collins, R.E, Horton, J.R, Cheng, X.
登録日2007-11-02
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules.
Nat.Struct.Mol.Biol., 15, 2008
7TD5
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BU of 7td5 by Molmil
Structure of human PRC2-EZH1 containing phosphorylated SUZ12
分子名称: Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, Polycomb protein SUZ12, ...
著者Gong, L, Jiao, L, Liu, X.
登録日2021-12-30
公開日2022-11-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.994 Å)
主引用文献CK2-mediated phosphorylation of SUZ12 promotes PRC2 function by stabilizing enzyme active site.
Nat Commun, 13, 2022
8SPS
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BU of 8sps by Molmil
High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b
分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2023-05-03
公開日2023-06-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
5B2I
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Human nucleosome containing CpG unmethylated DNA
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S.
登録日2016-01-16
公開日2016-06-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
3W99
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BU of 3w99 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H4 N-terminal region
分子名称: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2013-04-01
公開日2013-08-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
7V6Q
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BU of 7v6q by Molmil
Crystal structure of sNASP-ASF1A-H3.1-H4 complex
分子名称: GLYCEROL, Histone H3.1, Histone H4, ...
著者Liu, C.P, Xu, R.M.
登録日2021-08-20
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Distinct histone H3-H4 binding modes of sNASP reveal the basis for cooperation and competition of histone chaperones.
Genes Dev., 35, 2021
3W96
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BU of 3w96 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H2A N-terminal region
分子名称: 146-mer DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2013-04-01
公開日2013-08-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
8SWI
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BU of 8swi by Molmil
Crystal structure of legAS4 from Legionella pneumophila subsp. pneumophila with histone H3 (1-12)peptide
分子名称: Eukaryotic huntingtin interacting protein B, Histone H3 peptided, S-ADENOSYL-L-HOMOCYSTEINE
著者Xu, C, Chung, I.Y.W, Cygler, M.
登録日2023-05-18
公開日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The SET and ankyrin domains of the secreted Legionella pneumophila histone methyltransferase work together to modify host chromatin.
Mbio, 14, 2023
8H1T
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BU of 8h1t by Molmil
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
分子名称: DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ...
著者Ge, W, Yu, C, Xu, R.M.
登録日2022-10-04
公開日2023-02-01
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
Nature, 616, 2023
6LER
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BU of 6ler by Molmil
169 bp nucleosome harboring non-identical cohesive DNA termini.
分子名称: CALCIUM ION, DNA (169-MER), Histone H2A type 1-B/E, ...
著者Sharma, D, Adhireksan, Z, Lee, P.L, Davey, C.A.
登録日2019-11-26
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
3AZN
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BU of 3azn by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H4K91Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
2X0L
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BU of 2x0l by Molmil
Crystal structure of a neuro-specific splicing variant of human histone lysine demethylase LSD1.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, HISTONE H3 PEPTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
著者Zibetti, C, Adamo, A, Binda, C, Forneris, F, Verpelli, C, Ginelli, E, Mattevi, A, Sala, C, Battaglioli, E.
登録日2009-12-15
公開日2010-03-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Alternative Splicing of the Histone Demethylase Lsd1/Kdm1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System.
J.Neurosci., 30, 2010
3AZE
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BU of 3aze by Molmil
Crystal Structure of Human Nucleosome Core Particle Containing H3K64Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
6PA1
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BU of 6pa1 by Molmil
Killer cell immunoglobulin-like receptor 2DL2 in complex with HLA-C*07:02
分子名称: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Moradi, S, Rossjohn, J, Vivian, J.P.
登録日2019-06-11
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Nat Commun, 12, 2021
7K63
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BU of 7k63 by Molmil
Cryo-EM structure of a chromatosome containing chimeric linker histone gH1.10-ncH1.4
分子名称: DNA (197-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Zhou, B.-R, Bai, Y.
登録日2020-09-18
公開日2020-11-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
8GRM
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BU of 8grm by Molmil
Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome
分子名称: COMMD3 protein, DNA (144-MER), DNA (145-MER), ...
著者Ai, H.S, Zebin, T, Zhihend, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L.
登録日2022-09-02
公開日2023-04-12
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
5J3V
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BU of 5j3v by Molmil
Crystal structure of human Karyopherin-beta2 bound to the histone H3 tail
分子名称: Histone H3, Transportin-1,Transportin-1
著者Soniat, M, Chook, Y.M.
登録日2016-03-31
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Karyopherin-beta 2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif.
Structure, 24, 2016
6T90
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BU of 6t90 by Molmil
OCT4-SOX2-bound nucleosome - SHL-6
分子名称: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ...
著者Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-10-25
公開日2020-05-06
最終更新日2020-07-08
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
8WG5
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BU of 8wg5 by Molmil
Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者Ai, H.S, He, Z.Z, Deng, Z.H, Liu, L.
登録日2023-09-20
公開日2023-12-27
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16
Nature Structural & Molecular Biology, 2024
3WA9
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BU of 3wa9 by Molmil
The nucleosome containing human H2A.Z.1
分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
著者Horikoshi, N, Sato, K, Shimada, K, Arimura, Y, Osakabe, A, Tachiwana, H, Iwasaki, W, Kagawa, W, Harata, M, Kimura, H, Kurumizaka, H.
登録日2013-04-30
公開日2013-12-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.07 Å)
主引用文献Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2
Acta Crystallogr.,Sect.D, 69, 2013
5GSU
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BU of 5gsu by Molmil
Crystal structure of nucleosome core particle consisting of human testis-specific histone variants, Th2A and Th2B
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
著者Kumarevel, T, Sivaraman, P.
登録日2016-08-17
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
7K60
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Cryo-EM structure of a chromatosome containing human linker histone H1.10
分子名称: DNA (197-MER), Histone H1.10, Histone H2A type 1-B/E, ...
著者Zhou, B.-R, Bai, Y.
登録日2020-09-17
公開日2020-11-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
8IEJ
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BU of 8iej by Molmil
RNF20-RNF40/hRad6A-Ub/nucleosome complex
分子名称: DNA (147-MER), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Ai, H, Deng, Z, Sun, M, Du, Y, Pan, M, Liu, L.
登録日2023-02-15
公開日2023-09-06
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023

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件を2024-07-03に公開中

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