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PDB: 451 件
4Z5T
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The nucleosome containing human H3.5
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H.
登録日2015-04-03
公開日2016-02-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.
Epigenetics Chromatin, 9, 2016
3AV2
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The human nucleosome structure containing the histone variant H3.3
分子名称: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H.
登録日2011-02-18
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
7E8D
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NSD2 E1099K mutant bound to nucleosome
分子名称: DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ...
著者Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K.
登録日2021-03-01
公開日2021-11-10
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
Nat Commun, 12, 2021
6M4G
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Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2
分子名称: DNA (93-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ...
著者Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q.
登録日2020-03-06
公開日2020-09-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2.
Embo J., 40, 2021
5AY8
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BU of 5ay8 by Molmil
Crystal structure of human nucleosome containing H3.Y
分子名称: CHLORIDE ION, DNA (146-MER), H3.Y, ...
著者Kujirai, T, Horikoshi, N, Sato, K, Maehara, K, Machida, S, Osakabe, A, Kimura, H, Ohkawa, Y, Kurumizaka, H.
登録日2015-08-10
公開日2016-04-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and function of human histone H3.Y nucleosome
Nucleic Acids Res., 44, 2016
3WKJ
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The nucleosome containing human TSH2B
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Urahama, T, Horikoshi, N, Osakabe, A, Tachiwana, H, Kurumizaka, H.
登録日2013-10-22
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human nucleosome containing the testis-specific histone variant TSH2B.
Acta Crystallogr.,Sect.F, 70, 2014
3X1S
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Crystal structure of the nucleosome core particle
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Sivaraman, P, Kumarevel, T.S.
登録日2014-11-27
公開日2015-09-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
3X1T
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Crystal structure of nucleosome core particle consisting of mouse testis specific histone variants H2aa and H2ba
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A, ...
著者Sivaraman, P, Kumarevel, T.S.
登録日2014-11-27
公開日2015-09-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.808 Å)
主引用文献Structural and functional analyses of nucleosome complexes with mouse histone variants TH2a and TH2b, involved in reprogramming
Biochem.Biophys.Res.Commun., 464, 2015
8GUI
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Bre1-nucleosome complex (Model I)
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ...
著者Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T.
登録日2022-09-12
公開日2023-09-20
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structure of the human Bre1 complex bound to the nucleosome.
Nat Commun, 15, 2024
5XF5
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration)
分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
2QQS
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BU of 2qqs by Molmil
JMJD2A tandem tudor domains in complex with a trimethylated histone H4-K20 peptide
分子名称: JmjC domain-containing histone demethylation protein 3A, METHYLATED HISTONE H4 PEPTIDE
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
5GT0
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BU of 5gt0 by Molmil
Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
著者Kumarevel, T, Sivaraman, P.
登録日2016-08-18
公開日2017-02-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
分子名称: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
著者Bao, H, Huang, H.
登録日2021-08-04
公開日2022-04-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.834 Å)
主引用文献NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
7XVM
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BU of 7xvm by Molmil
Crystal Structure of Nucleosome-H5 Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A.
登録日2022-05-24
公開日2023-05-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
6K1J
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Human nucleosome core particle with H2A.X variant
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2AX, ...
著者Sharma, D, De Falco, L, Davey, C.A.
登録日2019-05-10
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome.
Nat Commun, 10, 2019
8EVH
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BU of 8evh by Molmil
CX3CR1 nucleosome and wild type PU.1 complex
分子名称: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
著者Lian, T, Guan, R, Bai, Y.
登録日2022-10-20
公開日2023-11-01
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
7K61
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Cryo-EM structure of 197bp nucleosome aided by scFv
分子名称: DNA (197-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Zhou, B.-R, Bai, Y.
登録日2020-09-17
公開日2020-11-25
最終更新日2021-01-20
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms.
Mol.Cell, 81, 2021
5GXQ
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BU of 5gxq by Molmil
The crystal structure of the nucleosome containing H3.6
分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Taguchi, H, Xie, Y, Horikoshi, N, Kurumizaka, H.
登録日2016-09-19
公開日2017-04-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
Biochemistry, 56, 2017
7COW
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BU of 7cow by Molmil
353 bp di-nucleosome harboring cohesive DNA termini with linker histone H1.0
分子名称: CALCIUM ION, CHLORIDE ION, DNA (353-MER), ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2020-08-05
公開日2021-08-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
5XF4
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Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (S,S-configuration)
分子名称: (1S,2S)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
8XBW
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BU of 8xbw by Molmil
The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome
分子名称: DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-12-07
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
3AZM
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Crystal Structure of Human Nucleosome Core Particle Containing H4K79Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
3AZJ
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Crystal Structure of Human Nucleosome Core Particle Containing H4K44Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-25
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
5ZGC
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Crystal Structure of SIRT3 in complex with H4K16bhb peptide
分子名称: Histone H4K16bhb peptide, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ...
著者Li, H, Zhang, X.
登録日2018-03-08
公開日2019-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of SIRT3 in complex with H4K16bhb peptide
To be published
3AYW
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Crystal Structure of Human Nucleosome Core Particle Containing H3K56Q mutation
分子名称: 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ...
著者Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2011-05-19
公開日2011-09-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011

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