7XCT
Cryo-EM structure of Dot1L and H2BK34ub-H3K79Nle nucleosome 2:1 complex
Summary for 7XCT
Entry DOI | 10.2210/pdb7xct/pdb |
EMDB information | 33127 |
Descriptor | Ubiquitin, Histone H4, Histone H2A, ... (9 entities in total) |
Functional Keywords | complex, dot1l, h2bk34ub, nucleosome, nuclear protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 14 |
Total formula weight | 271315.24 |
Authors | |
Primary citation | Ai, H.,Sun, M.,Liu, A.,Sun, Z.,Liu, T.,Cao, L.,Liang, L.,Qu, Q.,Li, Z.,Deng, Z.,Tong, Z.,Chu, G.,Tian, X.,Deng, H.,Zhao, S.,Li, J.B.,Lou, Z.,Liu, L. H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity. Nat.Chem.Biol., 18:972-980, 2022 Cited by PubMed: 35739357DOI: 10.1038/s41589-022-01067-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.72 Å) |
Structure validation
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