9CC0
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8YR3
| Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | Descriptor: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | Authors: | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | Deposit date: | 2024-03-20 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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8Y8H
| Structure of HCoV-HKU1C spike in the glycan-activated-2up conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Lu, Y.C, Zhang, X, Wang, H.F, Sun, L, Yang, H.T. | Deposit date: | 2024-02-06 | Release date: | 2024-07-17 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | TMPRSS2 and glycan receptors synergistically facilitate coronavirus entry. Cell, 187, 2024
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8Y8K
| The structure of hAE3 | Descriptor: | Anion exchange protein 3 | Authors: | Jian, L, Zhang, Q, Yao, D, Wang, Q, Xia, Y, Qin, A, Cao, Y. | Deposit date: | 2024-02-06 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | The structural insight into the functional modulation of human anion exchanger 3. Nat Commun, 15, 2024
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8YF6
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9AYW
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8YWW
| The structure of HKU1-B S protein with bsAb1 | Descriptor: | H4B6 heavy chain, H4B6 light chain, Spike glycoprotein, ... | Authors: | Xia, L.Y, Zhang, Y.Y, Zhou, Q. | Deposit date: | 2024-04-01 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | A novel bispecific antibody targeting two overlapping epitopes in RBD improves neutralizing potency and breadth against SARS-CoV-2. Emerg Microbes Infect, 13, 2024
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8YVG
| canine immunoproteasome 20S subunit in complex with compound 1 | Descriptor: | Proteasome subunit alpha type, Proteasome subunit beta, Proteasome subunit beta type-8, ... | Authors: | Kashima, A, Arai, Y. | Deposit date: | 2024-03-28 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
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8Y9C
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8ZGT
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8YVP
| canine immunoproteasome 20S subunit in complex with compound 1 | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | Authors: | Kashima, A, Arai, Y. | Deposit date: | 2024-03-29 | Release date: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor. Bioorg.Med.Chem., 109, 2024
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8ZJ2
| Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex | Descriptor: | Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M. | Deposit date: | 2024-05-14 | Release date: | 2024-06-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (4.66 Å) | Cite: | RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state. J.Biol.Chem., 300, 2024
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9B6D
| Cryo-EM structure of the mouse TRPM8 channel in the ligand-free desensitized state | Descriptor: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 8 | Authors: | Yin, Y, Park, C.-G, Zhang, F, Fedor, J, Feng, S, Suo, Y, Im, W, Lee, S.-Y. | Deposit date: | 2024-03-25 | Release date: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. Sci Adv, 10, 2024
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8Z3S
| Activation mechanism and novel binding site of the BKCa channel activator CTIBD | Descriptor: | 4-[4-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Lee, N, Kim, S, Jo, H, Lee, N.Y, Jin, M.S, Park, C.S. | Deposit date: | 2024-04-16 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Activation mechanism and novel binding sites of the BK Ca channel activator CTIBD. Life Sci Alliance, 7, 2024
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9CEO
| Caulobacter crescentus FljJM flagellar filament (asymmetrical) | Descriptor: | Flagellin FljM | Authors: | Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. | Deposit date: | 2024-06-26 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
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9CK3
| Cryo-EM structure of in-vitro alpha-synuclein fibril | Descriptor: | Alpha-synuclein | Authors: | Sanchez, J.C, Borcik, C.G, Tonelli, M, Sibert, B, Rienstra, C.M, Wright, E.R. | Deposit date: | 2024-07-08 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.04 Å) | Cite: | Multimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils To Be Published
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9ENC
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8YS2
| Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA1-2 | Descriptor: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | Authors: | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | Deposit date: | 2024-03-22 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes. Nat Commun, 15, 2024
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9B8Q
| Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, peripheral stalks | Descriptor: | V-type proton ATPase 116 kDa subunit a isoform 1, V-type proton ATPase subunit C 1, V-type proton ATPase subunit E 1, ... | Authors: | Coupland, C.E, Rubinstein, J.L. | Deposit date: | 2024-03-31 | Release date: | 2024-06-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles. Science, 385, 2024
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8Y4B
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9BRB
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8YS4
| Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA3-5 | Descriptor: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | Authors: | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | Deposit date: | 2024-03-22 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes. Nat Commun, 15, 2024
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9IJA
| A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex | Descriptor: | 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, CHOLESTEROL, Taste receptor type 2 member 14 | Authors: | Yuan, Q, Duan, J, Tao, L, Xu, E.H. | Deposit date: | 2024-06-21 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist. Cell Res., 2024
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8Z4J
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9AVV
| Bovine adult muscle nAChR resting state | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ... | Authors: | Li, H, Hibbs, R.E. | Deposit date: | 2024-03-05 | Release date: | 2024-07-31 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.09 Å) | Cite: | Structural switch in acetylcholine receptors in developing muscle. Nature, 632, 2024
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