8YWW

The structure of HKU1-B S protein with bsAb1

Summary for 8YWW

• Entry DOI: 10.2210/pdb8yww/pdb
• EMDB information: 39645
• Descriptor: Spike glycoprotein, H4B6 heavy chain, H4B6 light chain, ... (4 entities in total)
• Functional Keywords: sars-cov-2, antibody, viral protein/immune system, viral protein-immune system complex
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 8
• Total formula weight: 521542.63

Authors

Xia, L.Y.,Zhang, Y.Y.,Zhou, Q. (deposition date: 2024-04-01, release date: 2024-07-31)

• Primary citation: Sun, H.,Xia, L.,Li, J.,Zhang, Y.,Zhang, G.,Huang, P.,Wang, X.,Cui, Y.,Fang, T.,Fan, P.,Zhou, Q.,Chi, X.,Yu, C.; A novel bispecific antibody targeting two overlapping epitopes in RBD improves neutralizing potency and breadth against SARS-CoV-2.; Emerg Microbes Infect, 13:2373307-2373307, 2024; PubMed: 38953857; DOI: 10.1080/22221751.2024.2373307

Experimental method

ELECTRON MICROSCOPY (2.7 Å)