8YWW

The structure of HKU1-B S protein with bsAb1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Spike glycoprotein	polymer	1210	134104.0	3	UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601)	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2)	S glycoprotein,E2,Peplomer protein
2	D, G (E, G)	H4B6 heavy chain	polymer	218	23023.8	2		Homo sapiens (human)
3	E, F (D, F)	H4B6 light chain	polymer	212	23399.9	2		Homo sapiens (human)
4	H (H)	the scfv of H4D12	polymer	245	26383.2	1		Homo sapiens (human)

Sequence modifications

A, B, C: 1 - 1210 (UniProt: P0DTC2)

PDB	External Database	Details
Ile 19	Thr 19	variant
His 78	Arg 78	conflict
Val 79	Phe 79	conflict
Asp 142	Gly 142	variant
Gly 213	Val 213	variant
Asp 339	Gly 339	variant
Phe 371	Ser 371	variant
Pro 373	Ser 373	variant
Phe 375	Ser 375	variant
Ala 376	Thr 376	variant
Asn 405	Asp 405	variant
Ser 408	Arg 408	variant
Asn 417	Lys 417	variant
Lys 440	Asn 440	variant
Arg 452	Leu 452	variant
Asn 477	Ser 477	variant
Lys 478	Thr 478	variant
Ala 484	Glu 484	variant
Val 486	Phe 486	variant
Arg 498	Gln 498	variant
Tyr 501	Asn 501	variant
His 505	Tyr 505	variant
Gly 614	Asp 614	variant
Tyr 655	His 655	variant
Ser 658	Asn 658	conflict
Lys 679	Asn 679	variant
His 681	Pro 681	variant
Gly 682	Arg 682	conflict
Ser 683	Arg 683	conflict
Ser 685	Arg 685	conflict
Lys 764	Asn 764	variant
Tyr 796	Asp 796	variant
Pro 817	Phe 817	conflict
Pro 892	Ala 892	conflict
Pro 899	Ala 899	conflict
Pro 942	Ala 942	conflict
His 954	Gln 954	variant
Lys 969	Asn 969	variant
Pro 986	Lys 986	variant
Pro 987	Val 987	variant
Gly 1209	Tyr 1209	conflict
Ser 1210	Ile 1210	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	521542.6
All*	Total formula weight	521542.6

*Water molecules are not included.