9IJA

A local Cryo-EM structure of Bitter taste receptor TAS2R14 with Gi complex

This is a non-PDB format compatible entry.

Summary for 9IJA

• Entry DOI: 10.2210/pdb9ija/pdb
• EMDB information: 60627
• Descriptor: Taste receptor type 2 member 14, 4-methyl-N-[(2M)-2-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine, CHOLESTEROL (3 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 36907.99

Authors

Yuan, Q.,Duan, J.,Tao, L.,Xu, E.H. (deposition date: 2024-06-21, release date: 2024-07-24, Last modification date: 2024-10-16)

• Primary citation: Tao, L.,Wang, D.,Yuan, Q.,Zhao, F.,Zhang, Y.,Du, T.,Shen, S.,Xu, H.E.,Li, Y.,Yang, D.,Duan, J.; Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist.; Cell Res., 34:735-738, 2024; PubMed: 38969802; DOI: 10.1038/s41422-024-00995-4

Experimental method

ELECTRON MICROSCOPY (3.05 Å)