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8FQA	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-03-06 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.35 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ2	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPS	GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.38 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ6	LBD of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ3	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform N619K mutant of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg/N619K) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ1	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) Descriptor: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (5.59 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPX	Crystal structure of tumor related RhoA mutant A161P in complex with GDP Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Lin, Y, Zheng, Y. Deposit date: 2023-01-05 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Tumor related RhoA mutants interact with effectors in the GDP-bound state To Be Published
8FPW	Crystal structure of tumor related RhoA mutant A161V in complex with GDP Descriptor: 1,4-DIETHYLENE DIOXIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... Authors: Lin, Y, Zheng, Y. Deposit date: 2023-01-05 Release date: 2024-06-05 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Tumor related RhoA mutants interact with effectors in the GDP-bound state To Be Published
8FP5	CDK2 liganded with ATP and Mg2+ Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cyclin-dependent kinase 2, ... Authors: Schonbrunn, E, Sun, L. Deposit date: 2023-01-04 Release date: 2023-05-31 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun, 14, 2023
8FPF	Heterodimeric ABC transporter BmrCD in the inward-facing conformation bound to ATP: BmrCD_IF-ATP Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH, ... Authors: Qingyu, T, Hassane, M. Deposit date: 2023-01-04 Release date: 2023-11-22 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter Nat Commun, 14, 2023
8FP7	Crystal structure of hen egg white lysozyme Descriptor: Lysozyme C, SODIUM ION Authors: Lima, L.M.T.R, Ramos, N.G. Deposit date: 2023-01-04 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of hen egg white lysozyme To Be Published
8FP6	Crystal structure of hen egg white lysozyme Descriptor: Lysozyme C, SODIUM ION Authors: Lima, L.M.T.R, Ramos, N.G. Deposit date: 2023-01-04 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of hen egg white lysozyme To be published
8FP8	Crystal structure of hen egg white lysozyme Descriptor: Lysozyme C, SODIUM ION Authors: Lima, L.M.T.R, Ramos, N.G. Deposit date: 2023-01-04 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of hen egg white lysozyme To Be Published
8FPD	Crystal structure of hen egg white lysozyme Descriptor: Lysozyme C, SODIUM ION Authors: Lima, L.M.T.R, Ramos, N.G. Deposit date: 2023-01-04 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of hen egg white lysozyme To Be Published
8FPB	Crystal structure of hen egg white lysozyme Descriptor: Lysozyme C, SODIUM ION Authors: Lima, L.M.T.R, Ramos, N.G. Deposit date: 2023-01-04 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of hen egg white lysozyme To Be Published
8FPC	Conformation 1 of the ligand binding domain (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP4	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPH	Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP9	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.44 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPL	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPK	LBD conformation 1 of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) Descriptor: 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.76 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPG	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.32 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8C4C	F-actin decorated by SipA497-669 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Yuan, B, Wald, J, Marlovits, T.C. Deposit date: 2023-01-03 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis for subversion of host cell actin cytoskeleton during Salmonella infection. Sci Adv, 9, 2023
8C4E	F-actin decorated by SipA426-685 Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... Authors: Yuan, B, Wald, J, Marlovits, T.C. Deposit date: 2023-01-03 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structural basis for subversion of host cell actin cytoskeleton during Salmonella infection. Sci Adv, 9, 2023
8FP3	PKCeta kinase domain in complex with compound 11 Descriptor: (3P)-3-{4-[(3R,5S)-3-amino-5-methylpiperidin-1-yl]-6-chloro-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile, Protein kinase C eta type Authors: Johnson, E. Deposit date: 2023-01-03 Release date: 2023-04-05 Last modified: 2023-04-26 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Design and Synthesis of Functionally Active 5-Amino-6-Aryl Pyrrolopyrimidine Inhibitors of Hematopoietic Progenitor Kinase 1. J.Med.Chem., 66, 2023

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