6V62
 
 | | SETD3 double mutant (N255F/W273A) in Complex with an Actin Peptide with His73 Replaced with Lysine | | Descriptor: | 1,2-ETHANEDIOL, Actin, cytoplasmic 1, ... | | Authors: | Dai, S, Horton, J.R, Cheng, X. | | Deposit date: | 2019-12-04 | | Release date: | 2020-01-15 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
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8QSO
 | | Crystal structure of human Mcl-1 in complex with compound 1 | | Descriptor: | (13S,16R,19S)-16-benzyl-43-ethoxy-N-methyl-7,11,14,17-tetraoxo-13-phenyl-5-oxa-2,8,12,15,18-pentaaza-1(1,4),4(1,2)-dibenzena-9(1,4)-cyclohexanacycloicosaphane-19-carboxamide, Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Hekking, K.F.W, Gremmen, S, Maroto, S, Keefe, A.D, Zhang, Y. | | Deposit date: | 2023-10-10 | | Release date: | 2024-02-14 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.106 Å) | | Cite: | Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
J.Med.Chem., 67, 2024
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8R3E
 | | Huntingtin, 1-17, MBP-N | | Descriptor: | Maltodextrin-binding protein, ZINC ION | | Authors: | Steinbacher, S, Toledo-Sherman, L, Dominguez, C. | | Deposit date: | 2023-11-08 | | Release date: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Post-translational modifications in the first 17 amino acids of huntingtin influence self-association and interaction with membranes
To Be Published
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8R2O
 | | Huntingtin-Q17, 1-66, N-MBP fusion | | Descriptor: | Maltodextrin-binding protein,Huntingtin, myristoylated N-terminal fragment, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Toledo-Sherman, L, Dominguez, C. | | Deposit date: | 2023-11-07 | | Release date: | 2024-09-18 | | Method: | X-RAY DIFFRACTION (3.23 Å) | | Cite: | Post-translational modifications in the first 17 amino acids of huntingtin influence self-association and interaction with membranes
To Be Published
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6V63
 | | SETD3 WT in Complex with an Actin Peptide with His73 Replaced with Glutamine | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Actin, ... | | Authors: | Dai, S, Horton, J.R, Cheng, X. | | Deposit date: | 2019-12-04 | | Release date: | 2020-01-22 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation.
J.Biol.Chem., 295, 2020
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8AX8
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8C8F
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8CE0
 | | N-terminal domain of human apolipoprotein E | | Descriptor: | GLYCEROL, Maltodextrin-binding protein,Apolipoprotein E | | Authors: | Marek, M, Nemergut, M. | | Deposit date: | 2023-02-01 | | Release date: | 2023-07-19 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Mol Neurodegener, 18, 2023
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8CDY
 | | N-terminal domain of human apolipoprotein E | | Descriptor: | Maltodextrin-binding protein,Apolipoprotein E | | Authors: | Marek, M, Nemergut, M. | | Deposit date: | 2023-02-01 | | Release date: | 2023-07-19 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Mol Neurodegener, 18, 2023
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8C5L
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2OFS
 | | Crystal structure of human CD59 | | Descriptor: | CD59 glycoprotein | | Authors: | Davies, C. | | Deposit date: | 2007-01-04 | | Release date: | 2007-05-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex.
Acta Crystallogr.,Sect.D, 63, 2007
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8AX9
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2NVU
 | | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | | Authors: | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | | Deposit date: | 2006-11-13 | | Release date: | 2007-01-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
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2OBG
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2OK2
 | | MutS C-terminal domain fused to Maltose Binding Protein | | Descriptor: | Maltose-binding periplasmic protein, DNA mismatch repair protein mutS fusion protein, SULFATE ION, ... | | Authors: | Putnam, C.D, Mendillo, M.L, Kolodner, R.D. | | Deposit date: | 2007-01-15 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Escherichia coli MutS Tetramerization Domain Structure Reveals That Stable Dimers but Not Tetramers Are Essential for DNA Mismatch Repair in Vivo.
J.Biol.Chem., 282, 2007
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2R6G
 | | The Crystal Structure of the E. coli Maltose Transporter | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Maltose transport system permease protein malF, Maltose transport system permease protein malG, ... | | Authors: | Oldham, M.L, Khare, D, Quiocho, F.A, Davidson, A.L, Chen, J. | | Deposit date: | 2007-09-05 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of a catalytic intermediate of the maltose transporter.
Nature, 450, 2007
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2V93
 | | EQUILLIBRIUM MIXTURE OF OPEN AND PARTIALLY-CLOSED SPECIES IN THE APO STATE OF MALTODEXTRIN-BINDING PROTEIN BY PARAMAGNETIC RELAXATION ENHANCEMENT NMR | | Descriptor: | 1-(1-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)PYRROLIDINE-2,5-DIONE, MALTOSE-BINDING PERIPLASMIC PROTEIN | | Authors: | Clore, G.M, Tang, C. | | Deposit date: | 2007-08-21 | | Release date: | 2007-11-06 | | Last modified: | 2024-11-20 | | Method: | SOLUTION NMR | | Cite: | Open-to-Closed Transition in Apo Maltose-Binding Protein Observed by Paramagnetic NMR.
Nature, 449, 2007
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3SET
 | | Ni-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | | Descriptor: | Maltose-binding periplasmic protein, NICKEL (II) ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3SES
 | | Cu-mediated Dimer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization | | Descriptor: | CHLORIDE ION, COPPER (II) ION, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3SEW
 | | Zn-mediated Polymer of Maltose-binding Protein A216H/K220H by Synthetic Symmetrization (Form I) | | Descriptor: | CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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8ART
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3SEV
 | | Zn-mediated Trimer of Maltose-binding Protein E310H/K314H by Synthetic Symmetrization | | Descriptor: | CHLORIDE ION, Maltose-binding periplasmic protein, ZINC ION, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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3SER
 | | Zn-mediated Polymer of Maltose-binding Protein K26H/K30H by Synthetic Symmetrization | | Descriptor: | CALCIUM ION, CHLORIDE ION, Maltose-binding periplasmic protein, ... | | Authors: | Zhao, M, Soriaga, A.B, Laganowsky, A, Sawaya, M.R, Cascio, D, Yeates, T.O. | | Deposit date: | 2011-06-11 | | Release date: | 2011-09-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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8B0H
 | | 2C9, C5b9-CD59 cryoEM structure | | Descriptor: | CD59 glycoprotein, Complement C5, Complement component C6, ... | | Authors: | Couves, E.C, Gardner, S, Bubeck, D. | | Deposit date: | 2022-09-07 | | Release date: | 2023-02-22 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
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3DM0
 | | Maltose Binding Protein fusion with RACK1 from A. thaliana | | Descriptor: | 1,2-ETHANEDIOL, Maltose-binding periplasmic protein fused with RACK1, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Ullah, H, Scappini, E.L, Moon, A.F, Williams, L.V, Armstrong, D.L, Pedersen, L.C. | | Deposit date: | 2008-06-30 | | Release date: | 2008-09-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana.
Protein Sci., 17, 2008
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