8CE0

N-terminal domain of human apolipoprotein E

Summary for 8CE0

Entry DOI	10.2210/pdb8ce0/pdb
Descriptor	Maltodextrin-binding protein,Apolipoprotein E, GLYCEROL (3 entities in total)
Functional Keywords	apolipoprotein e, n-terminal domain, lipid transport
Biological source	Escherichia coli More
Total number of polymer chains	1
Total formula weight	75209.97
Authors	Marek, M.,Nemergut, M. (deposition date: 2023-02-01, release date: 2023-07-19)
Primary citation	Nemergut, M.,Marques, S.M.,Uhrik, L.,Vanova, T.,Nezvedova, M.,Gadara, D.C.,Jha, D.,Tulis, J.,Novakova, V.,Planas-Iglesias, J.,Kunka, A.,Legrand, A.,Hribkova, H.,Pospisilova, V.,Sedmik, J.,Raska, J.,Prokop, Z.,Damborsky, J.,Bohaciakova, D.,Spacil, Z.,Hernychova, L.,Bednar, D.,Marek, M. Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate. Mol Neurodegener, 18:38-38, 2023 Cited by PubMed: 37280636 DOI: 10.1186/s13024-023-00620-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation