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3C9C
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BU of 3c9c by Molmil
Structural Basis of Histone H4 Recognition by p55
Descriptor: CADMIUM ION, Chromatin assembly factor 1 p55 subunit, Histone H4, ...
Authors:Song, J.J, Garlick, J.D, Kingston, R.E.
Deposit date:2008-02-15
Release date:2008-05-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of histone H4 recognition by p55.
Genes Dev., 22, 2008
7OW7
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BU of 7ow7 by Molmil
EIF6-bound large subunit of the human ribosome
Descriptor: 28S rRNA, 5.8S ribosomal RNA, 5S rRNA, ...
Authors:Faille, A, Warren, A.J.
Deposit date:2021-06-16
Release date:2022-10-05
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of human EIF6-bound large ribosomal subunit
To Be Published
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6IP8
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BU of 6ip8 by Molmil
Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6ZYM
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BU of 6zym by Molmil
Human C Complex Spliceosome - High-resolution CORE
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Corepressor interacting with RBPJ 1, ...
Authors:Bertram, K, Kastner, B.
Deposit date:2020-08-02
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
8FKU
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BU of 8fku by Molmil
Human nucleolar pre-60S ribosomal subunit (State C2)
Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FKT
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BU of 8fkt by Molmil
Human nucleolar pre-60S ribosomal subunit (State C1)
Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
6IP5
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BU of 6ip5 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
Deposit date:2018-11-02
Release date:2019-05-29
Last modified:2019-11-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
8EQV
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BU of 8eqv by Molmil
Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2
Descriptor: Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ...
Authors:Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C.
Deposit date:2022-10-09
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:To be updated
To Be Published
6CIX
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BU of 6cix by Molmil
Lactam cyclised mimetic of a fragment of p21
Descriptor: p21
Authors:Wegener, K.L.
Deposit date:2018-02-25
Release date:2018-07-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
6CEJ
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BU of 6cej by Molmil
Solution structure of a 14mer fragment of the p21 protein
Descriptor: Cyclin-dependent kinase inhibitor 1
Authors:Wegener, K.L.
Deposit date:2018-02-12
Release date:2018-07-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
4R7A
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BU of 4r7a by Molmil
Crystal Structure of RBBP4 bound to PHF6 peptide
Descriptor: GLYCEROL, Histone-binding protein RBBP4, PHD finger protein 6
Authors:Liu, Z, Li, F, Zhang, B, Li, S, Wu, J, Shi, Y.
Deposit date:2014-08-27
Release date:2015-01-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex
J.Biol.Chem., 290, 2015
4WKM
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BU of 4wkm by Molmil
AmpR effector binding domain from Citrobacter freundii bound to UDP-MurNAc-pentapeptide
Descriptor: ALA-FGA-API-DAL-DAL, GLYCEROL, LysR family transcriptional regulator, ...
Authors:Vadlamani, G, Reeve, T.M, Mark, B.L.
Deposit date:2014-10-02
Release date:2014-12-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The beta-Lactamase Gene Regulator AmpR Is a Tetramer That Recognizes and Binds the d-Ala-d-Ala Motif of Its Repressor UDP-N-acetylmuramic Acid (MurNAc)-pentapeptide.
J.Biol.Chem., 290, 2015
2XAS
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BU of 2xas by Molmil
Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2580, 14e)
Descriptor: 3-[4-({N-[(BENZYLOXY)CARBONYL]-L-PHENYLALANYL}AMINO)PHENYL]PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
4WVY
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BU of 4wvy by Molmil
Double-heterohexameric rings of full-length Rvb1(ATP)/Rvb2(apo)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Hopfner, K.-P, Lakomek, K.
Deposit date:2014-11-08
Release date:2015-02-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.64 Å)
Cite:Structural Basis for Dodecameric Assembly States and Conformational Plasticity of the Full-Length AAA+ ATPases Rvb1Rvb2.
Structure, 23, 2015
2XAF
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BU of 2xaf by Molmil
Crystal structure of LSD1-CoREST in complex with para-bromo-(+)-cis-2- phenylcyclopropyl-1-amine
Descriptor: 3-(4-BROMOPHENYL)PROPANAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAH
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BU of 2xah by Molmil
Crystal structure of LSD1-CoREST in complex with (+)-trans-2- phenylcyclopropyl-1-amine
Descriptor: 3-PHENYLPROPANAL, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAQ
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BU of 2xaq by Molmil
Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b)
Descriptor: 3-{4-[(PHENYLCARBONYL)AMINO]PHENYL}PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAG
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BU of 2xag by Molmil
Crystal structure of LSD1-CoREST in complex with para-bromo-(-)-trans- 2-phenylcyclopropyl-1-amine
Descriptor: 3-(4-BROMOPHENYL)PROPANAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
2XAJ
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BU of 2xaj by Molmil
Crystal structure of LSD1-CoREST in complex with (-)-trans-2- phenylcyclopropyl-1-amine
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, PHENYLETHYLENECARBOXYLIC ACID, ...
Authors:Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A.
Deposit date:2010-03-31
Release date:2010-05-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
1HOM
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BU of 1hom by Molmil
DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: ANTENNAPEDIA PROTEIN
Authors:Qian, Y.-Q, Billeter, M, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K.
Deposit date:1991-10-08
Release date:1993-10-31
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Determination of the three-dimensional structure of the Antennapedia homeodomain from Drosophila in solution by 1H nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 214, 1990
3R6S
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BU of 3r6s by Molmil
Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, HEXANE-1,6-DIOL, transcription regulator
Authors:Jungwirth, B, Pojer, F.
Deposit date:2011-03-22
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP
To be Published
4EV0
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BU of 4ev0 by Molmil
Crystal Structure of Thermus thermophilus Catabolite Activator Protein
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
Authors:Hudson, B.P, Turo, K, Birktoft, J.J, Lawson, C.L.
Deposit date:2012-04-25
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Crystal Structure of T. thermophilius Catabolite Activator Protein
To be Published
5OSM
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BU of 5osm by Molmil
Cdk2(F80C, C177A) with covalent adduct at C80
Descriptor: Cyclin-dependent kinase 2, methyl 1-propanoyl-3,4-dihydro-2~{H}-quinoline-6-carboxylate
Authors:Craven, G, Morgan, R.M.L, Mann, D.J.
Deposit date:2017-08-17
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:High-Throughput Kinetic Analysis for Target-Directed Covalent Ligand Discovery.
Angew. Chem. Int. Ed. Engl., 57, 2018
4XK4
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BU of 4xk4 by Molmil
E. coli transcriptional regulator RUTR with dihydrouracil
Descriptor: DIHYDROPYRIMIDINE-2,4(1H,3H)-DIONE, HTH-type transcriptional regulator RutR
Authors:Shumilin, I.A, Cooper, D.R, Shabalin, I.G, Grabowski, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2015-01-09
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:E. COLI TRANSCRIPTIONAL REGULATOR RUTR WITH DIHYDROURACIL
to be published

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