4EYQ
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![BU of 4eyq by Molmil](/molmil-images/mine/4eyq) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 in complex with caffeic acid/3-(4-HYDROXY-PHENYL)PYRUVIC ACID | Descriptor: | 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, CAFFEIC ACID, Extracellular ligand-binding receptor | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
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4FD2
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![BU of 4fd2 by Molmil](/molmil-images/mine/4fd2) | Crystal structure of the C-terminal domain of ClpB | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB | Authors: | Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F. | Deposit date: | 2012-05-25 | Release date: | 2012-07-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for intersubunit signaling in a protein disaggregating machine. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F4R
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![BU of 4f4r by Molmil](/molmil-images/mine/4f4r) | Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop | Descriptor: | CHLORIDE ION, D-mannonate dehydratase, GLYCEROL, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI), Medical Structural Genomics of Pathogenic Protozoa (MSGPP) | Deposit date: | 2012-05-11 | Release date: | 2012-06-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop to be published
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4O2G
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![BU of 4o2g by Molmil](/molmil-images/mine/4o2g) | Crystal structure of carbomonoxy murine neuroglobin mutant V140W | Descriptor: | CARBON MONOXIDE, Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Avella, G, Savino, C, Vallone, B. | Deposit date: | 2013-12-17 | Release date: | 2014-06-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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4F06
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![BU of 4f06 by Molmil](/molmil-images/mine/4f06) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 RPB_2270 in complex with P-HYDROXYBENZOIC ACID | Descriptor: | Extracellular ligand-binding receptor, GLYCEROL, P-HYDROXYBENZOIC ACID, ... | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-03 | Release date: | 2012-08-15 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4F2V
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![BU of 4f2v by Molmil](/molmil-images/mine/4f2v) | Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165 | Descriptor: | DI(HYDROXYETHYL)ETHER, DODECYL-ALPHA-D-MALTOSIDE, De novo designed serine hydrolase | Authors: | Kuzin, A, Lew, S, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-08 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.493 Å) | Cite: | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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4EYK
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![BU of 4eyk by Molmil](/molmil-images/mine/4eyk) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris BisB5 in complex with 3,4-dihydroxy benzoic acid | Descriptor: | 1,2-ETHANEDIOL, 3,4-DIHYDROXYBENZOIC ACID, Twin-arginine translocation pathway signal | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2012-10-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J.Mol.Biol., 423, 2012
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4NZI
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![BU of 4nzi by Molmil](/molmil-images/mine/4nzi) | Crystal structure of murine neuroglobin mutant V140W | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Avella, G, Savino, C, Vallone, B. | Deposit date: | 2013-12-12 | Release date: | 2014-06-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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4NZG
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![BU of 4nzg by Molmil](/molmil-images/mine/4nzg) | Crystal Structure of the N-terminal domain of Moloney murine leukemia virus integrase, Northeast Structural Genomics Consortium Target OR3 | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, Integrase p46, ... | Authors: | Guan, R, Jiang, M, Janjua, H, Maglaqui, M, Zhao, L, Xiao, R, Acton, T.B, Everett, J.K, Roth, M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-12-12 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition. Proteins, 85, 2017
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4O07
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![BU of 4o07 by Molmil](/molmil-images/mine/4o07) | Identification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's disease | Descriptor: | 2,7,7-trimethyl-9-[8-(2-methylpropyl)-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl]-1,2,3,4,6,7,8,9-octahydro-5H-beta-carbolin-5-one, Heat shock protein HSP 90-alpha | Authors: | Zuccola, H.J, Ernst, J.T. | Deposit date: | 2013-12-13 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Identification of Novel HSP90 alpha / beta Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington's Disease. J.Med.Chem., 57, 2014
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4FBY
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![BU of 4fby by Molmil](/molmil-images/mine/4fby) | fs X-ray diffraction of Photosystem II | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Kern, J, Alonso-Mori, R, Hellmich, J, Tran, R, Hattne, J, Laksmono, H, Gloeckner, C, Echols, N, Sierra, R.G, Sellberg, J, Lassalle-Kaiser, B, Gildea, R.J, Glatzel, P, Grosse-Kunstleve, R.W, Latimer, M.J, Mcqueen, T.A, Difiore, D, Fry, A.R, Messerschmidt, M.M, Miahnahri, A, Schafer, D.W, Seibert, M.M, Sokaras, D, Weng, T.-C, Zwart, P.H, White, W.E, Adams, P.D, Bogan, M.J, Boutet, S, Williams, G.J, Messinger, J, Sauter, N.K, Zouni, A, Bergmann, U, Yano, J, Yachandra, V.K. | Deposit date: | 2012-05-23 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (6.56 Å) | Cite: | Room temperature femtosecond X-ray diffraction of photosystem II microcrystals. Proc.Natl.Acad.Sci.USA, 109, 2012
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4FCV
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![BU of 4fcv by Molmil](/molmil-images/mine/4fcv) | Crystal structure of the C-terminal domain of ClpB | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB | Authors: | Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F. | Deposit date: | 2012-05-25 | Release date: | 2012-07-18 | Last modified: | 2012-08-22 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for intersubunit signaling in a protein disaggregating machine. Proc.Natl.Acad.Sci.USA, 109, 2012
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4EYO
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![BU of 4eyo by Molmil](/molmil-images/mine/4eyo) | Crystal structure of solute binding protein of ABC transporter from Rhodopseudomonas palustris HaA2 in complex with p-coumaric acid | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Extracellular ligand-binding receptor | Authors: | Chang, C, Mack, J, Zerbs, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-01 | Release date: | 2012-05-30 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-Coumaric acid and related aromatic acids. Proteins, 81, 2013
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4O35
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![BU of 4o35 by Molmil](/molmil-images/mine/4o35) | Crystal structure of carbomonoxy murine neuroglobin mutant F106W | Descriptor: | 1,4-DIETHYLENE DIOXIDE, CARBON MONOXIDE, Neuroglobin, ... | Authors: | Avella, G, Savino, C, Vallone, B. | Deposit date: | 2013-12-18 | Release date: | 2014-06-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism. Acta Crystallogr.,Sect.D, 70, 2014
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4F80
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![BU of 4f80 by Molmil](/molmil-images/mine/4f80) | Crystal Structure of the human BTN3A1 ectodomain | Descriptor: | Butyrophilin subfamily 3 member A1 | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | Deposit date: | 2012-05-16 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.944 Å) | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies J.Biol.Chem., 287, 2012
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4FBG
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![BU of 4fbg by Molmil](/molmil-images/mine/4fbg) | Crystal structure of Treponema denticola trans-2-enoyl-CoA reductase in complex with NAD | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative reductase TDE_0597 | Authors: | Hu, K, Zhao, M, Zhang, T, Yang, S, Ding, J. | Deposit date: | 2012-05-23 | Release date: | 2012-11-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism Biochem.J., 449, 2013
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4O9C
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![BU of 4o9c by Molmil](/molmil-images/mine/4o9c) | Crystal structure of Beta-ketothiolase (PhaA) from Ralstonia eutropha H16 | Descriptor: | Acetyl-CoA acetyltransferase, COENZYME A | Authors: | Kim, E.J, Kim, J, Kim, S, Kim, K.J. | Deposit date: | 2014-01-02 | Release date: | 2014-12-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure and biochemical characterization of PhaA from Ralstonia eutropha, a polyhydroxyalkanoate-producing bacterium. Biochem.Biophys.Res.Commun., 452, 2014
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4FOI
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![BU of 4foi by Molmil](/molmil-images/mine/4foi) | |
4OM5
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![BU of 4om5 by Molmil](/molmil-images/mine/4om5) | Crystal structure of CTX A4 from Taiwan Cobra (Naja naja atra) | Descriptor: | Cytotoxin 4 | Authors: | Lin, C.C, Chang, C.I, Wu, W.G. | Deposit date: | 2014-01-26 | Release date: | 2014-06-11 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface. J.Biol.Chem., 289, 2014
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4F6A
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![BU of 4f6a by Molmil](/molmil-images/mine/4f6a) | High-resolution x-ray Structure of the tetramutant of BH1408 protein from Bacillus halodurans, Northeast Structural Genomics Consortium (NESG) Target BhR182 | Descriptor: | BH1408 protein, UNKNOWN LIGAND | Authors: | Kuzin, A, Neely, H, Odukwe, N, Seetharaman, J, Patel, P, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-14 | Release date: | 2012-06-13 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.009 Å) | Cite: | Northeast Structural Genomics Consortium Target BhR182 To be Published
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4F67
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![BU of 4f67 by Molmil](/molmil-images/mine/4f67) | Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target LgR82 | Descriptor: | UPF0176 protein lpg2838 | Authors: | Kuzin, A, Neely, H, Street, L, Odukwe, N, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-14 | Release date: | 2012-05-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast
Structural Genomics Consortium (NESG) Target LgR82 To be Published
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4OLG
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![BU of 4olg by Molmil](/molmil-images/mine/4olg) | Crystal structure of AmpC beta-lactamase in complex with covalently bound N-formyl 7-aminocephalosporanic acid | Descriptor: | (2R,5Z)-5-[(acetyloxy)methylidene]-2-[(1R)-1-(formylamino)-2-oxoethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, PHOSPHATE ION | Authors: | Shoichet, B.K, Barelier, S. | Deposit date: | 2014-01-23 | Release date: | 2014-05-28 | Last modified: | 2014-06-18 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Substrate deconstruction and the nonadditivity of enzyme recognition. J.Am.Chem.Soc., 136, 2014
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4FBH
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![BU of 4fbh by Molmil](/molmil-images/mine/4fbh) | Structure of RIP from barley seeds | Descriptor: | ADENOSINE MONOPHOSPHATE, Protein synthesis inhibitor I | Authors: | Lee, B.-G, Kim, M.K, Suh, S.W, Song, H.K. | Deposit date: | 2012-05-23 | Release date: | 2012-10-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism. Acta Crystallogr.,Sect.D, 68, 2012
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4FBC
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![BU of 4fbc by Molmil](/molmil-images/mine/4fbc) | Structure of mutant RIP from barley seeds in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Protein synthesis inhibitor I | Authors: | Lee, B.-G, Kim, M.K, Suh, S.W, Song, H.K. | Deposit date: | 2012-05-22 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structures of the ribosome-inactivating protein from barley seeds reveal a unique activation mechanism. Acta Crystallogr.,Sect.D, 68, 2012
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4FDB
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![BU of 4fdb by Molmil](/molmil-images/mine/4fdb) | Three-dimensional structure of the protein prib from ralstonia solanacearum at the resolution 1.8a. northeast structural genomics consortium target rsr213c | Descriptor: | ACETIC ACID, Probable primosomal replication protein n | Authors: | Kuzin, A, Neely, H, Seetharaman, J, Wang, H, Sahdev, S, Foote, E.L, Xiao, R, Liu, J, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2012-05-27 | Release date: | 2013-02-13 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional structure of the protein prib from ralstonia solanacearum at the resolution 1.8a. northeast structural genomics consortium target rsr213c To be Published
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