Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7MZ5
DownloadVisualize
BU of 7mz5 by Molmil
Cryo-EM structure of RTX-bound full-length TRPV1 in C2 state
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZA
DownloadVisualize
BU of 7mza by Molmil
Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZB
DownloadVisualize
BU of 7mzb by Molmil
Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZ7
DownloadVisualize
BU of 7mz7 by Molmil
Cryo-EM structure of minimal TRPV1 with 4 partially bound RTX
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZD
DownloadVisualize
BU of 7mzd by Molmil
Cryo-EM structure of minimal TRPV1 with RTX bound in C2 state
Descriptor: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2021-05-24
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2W
DownloadVisualize
BU of 7l2w by Molmil
cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state a
Descriptor: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2R
DownloadVisualize
BU of 7l2r by Molmil
Cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-open state
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2N
DownloadVisualize
BU of 7l2n by Molmil
Cryo-EM structure of RTX-bound full-length TRPV1 in C1 state
Descriptor: Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2L
DownloadVisualize
BU of 7l2l by Molmil
Cryo-EM structure of RTX-bound full-length TRPV1 in O1 state
Descriptor: Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2S
DownloadVisualize
BU of 7l2s by Molmil
cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-bound state
Descriptor: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2O
DownloadVisualize
BU of 7l2o by Molmil
Cryo-EM structure of RTX-bound full-length TRPV1 at pH 5.5
Descriptor: Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2J
DownloadVisualize
BU of 7l2j by Molmil
Cryo-EM structure of full-length TRPV1 at pH6c state
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, Transient receptor potential cation channel subfamily V member 1
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2T
DownloadVisualize
BU of 7l2t by Molmil
cryo-EM structure of DkTx-bound minimal TRPV1 in partial open state
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2P
DownloadVisualize
BU of 7l2p by Molmil
cryo-EM structure of unliganded minimal TRPV1
Descriptor: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2X
DownloadVisualize
BU of 7l2x by Molmil
cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state c
Descriptor: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, 1-deoxy-1-(methylamino)-D-allitol, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2M
DownloadVisualize
BU of 7l2m by Molmil
Cryo-EM structure of DkTx/RTX-bound full-length TRPV1
Descriptor: SODIUM ION, Tau-theraphotoxin-Hs1a, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2K
DownloadVisualize
BU of 7l2k by Molmil
Cryo-EM structure of full-length TRPV1 at pH6b state
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2I
DownloadVisualize
BU of 7l2i by Molmil
Cryo-EM structure of full-length TRPV1 at pH6a state
Descriptor: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, Transient receptor potential cation channel subfamily V member 1
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2U
DownloadVisualize
BU of 7l2u by Molmil
cryo-EM structure of DkTx-bound minimal TRPV1 in open state
Descriptor: (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2H
DownloadVisualize
BU of 7l2h by Molmil
Cryo-EM structure of unliganded full-length TRPV1 at neutral pH
Descriptor: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl tridecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7L2V
DownloadVisualize
BU of 7l2v by Molmil
cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state b
Descriptor: 6-deoxy-6-(methylamino)-D-galactitol, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
Authors:Zhang, K, Julius, D, Cheng, Y.
Deposit date:2020-12-17
Release date:2021-09-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7S8C
DownloadVisualize
BU of 7s8c by Molmil
Cryo-EM structure of human TRPV6 in complex with inhibitor econazole
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, ...
Authors:Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
Deposit date:2021-09-17
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12, 2021
7S8B
DownloadVisualize
BU of 7s8b by Molmil
Cryo-EM structure of human TRPV6 in complex with channel blocker ruthenium red
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ...
Authors:Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
Deposit date:2021-09-17
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12, 2021
7S89
DownloadVisualize
BU of 7s89 by Molmil
Open apo-state cryo-EM structure of human TRPV6 in cNW11 nanodiscs
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ...
Authors:Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
Deposit date:2021-09-17
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12, 2021
7S88
DownloadVisualize
BU of 7s88 by Molmil
Open apo-state cryo-EM structure of human TRPV6 in glyco-diosgenin detergent
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ...
Authors:Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
Deposit date:2021-09-17
Release date:2021-11-17
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.69 Å)
Cite:Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12, 2021

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon