7L2S
cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-bound state
Summary for 7L2S
Entry DOI | 10.2210/pdb7l2s/pdb |
EMDB information | 23139 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, ... (4 entities in total) |
Functional Keywords | trp channel, cryo-em, nanodisc, toxin, transport protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 296753.81 |
Authors | Zhang, K.,Julius, D.,Cheng, Y. (deposition date: 2020-12-17, release date: 2021-09-22, Last modification date: 2024-05-29) |
Primary citation | Zhang, K.,Julius, D.,Cheng, Y. Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184:5138-5150.e12, 2021 Cited by PubMed: 34496225DOI: 10.1016/j.cell.2021.08.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.71 Å) |
Structure validation
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