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7S89

Open apo-state cryo-EM structure of human TRPV6 in cNW11 nanodiscs

Summary for 7S89
Entry DOI10.2210/pdb7s89/pdb
Related7S88
EMDB information24890 24891
DescriptorTransient receptor potential cation channel subfamily V member 6, CHOLESTEROL HEMISUCCINATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ... (6 entities in total)
Functional Keywordstransient receptor potential v family member 6, trp, channel, cnw11, nanodiscs, human, trpv6, membrane protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight343996.71
Authors
Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (deposition date: 2021-09-17, release date: 2021-11-17)
Primary citationNeuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I.
Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
Nat Commun, 12:6284-6284, 2021
Cited by
PubMed: 34725357
DOI: 10.1038/s41467-021-26608-x
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.54 Å)
Structure validation

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