7L2W

cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state a

Summary for 7L2W

Entry DOI	10.2210/pdb7l2w/pdb
EMDB information	23143
Descriptor	Transient receptor potential cation channel subfamily V member 1, resiniferatoxin, (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, ... (5 entities in total)
Functional Keywords	trp channel, cryo-em, nanodisc, large cation, vanilloid agonist, transport protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	4
Total formula weight	296866.11
Authors	Zhang, K.,Julius, D.,Cheng, Y. (deposition date: 2020-12-17, release date: 2021-09-22, Last modification date: 2021-10-13)
Primary citation	Zhang, K.,Julius, D.,Cheng, Y. Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184:5138-, 2021 Cited by PubMed: 34496225 DOI: 10.1016/j.cell.2021.08.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.16 Å)

Structure validation