7L2I

Cryo-EM structure of full-length TRPV1 at pH6a state

Summary for 7L2I

Entry DOI	10.2210/pdb7l2i/pdb
EMDB information	23129
Descriptor	Transient receptor potential cation channel subfamily V member 1, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate (2 entities in total)
Functional Keywords	trp channel, cryo-em, nanodisc, full length, proton, transport protein
Biological source	Rattus norvegicus (Rat)
Total number of polymer chains	4
Total formula weight	383715.16
Authors	Zhang, K.,Julius, D.,Cheng, Y. (deposition date: 2020-12-17, release date: 2021-09-22, Last modification date: 2024-05-29)
Primary citation	Zhang, K.,Julius, D.,Cheng, Y. Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184:5138-, 2021 Cited by PubMed: 34496225 DOI: 10.1016/j.cell.2021.08.012 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation