7L2I
Cryo-EM structure of full-length TRPV1 at pH6a state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, D, B) | Transient receptor potential cation channel subfamily V member 1 | polymer | 842 | 95328.2 | 4 | UniProt (O35433) Pfam (PF00023) Pfam (PF00520) | Rattus norvegicus (Rat) | TrpV1,Capsaicin receptor,Osm-9-like TRP channel 1,OTRPC1,Vanilloid receptor 1,Vanilloid receptor type 1-like |
| 2 | E, F, G, H (A, C, D, B) | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate | non-polymer | 600.6 | 4 | Chemie (XJA) |
Sequence modifications
A, C, D, B: 2 - 838 (UniProt: O35433)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 381312.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2402.5 | |
| All* | Total formula weight | 383715.2 |
