2L4Z
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![BU of 2l4z by Molmil](/molmil-images/mine/2l4z) | NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82) | Descriptor: | DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION | Authors: | Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M. | Deposit date: | 2010-10-22 | Release date: | 2011-10-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8. J.Mol.Biol., 425, 2013
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2LEF
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![BU of 2lef by Molmil](/molmil-images/mine/2lef) | LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES | Descriptor: | DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) | Authors: | Li, X, Love, J.J, Case, D.A, Wright, P.E. | Deposit date: | 1998-10-13 | Release date: | 1998-10-21 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature, 376, 1995
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2LJ9
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![BU of 2lj9 by Molmil](/molmil-images/mine/2lj9) | |
2LJL
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1E99
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![BU of 1e99 by Molmil](/molmil-images/mine/1e99) | Human thymidylate kinase complexed with AZTMP and ADP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
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1E98
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![BU of 1e98 by Molmil](/molmil-images/mine/1e98) | Wild type human thymidylate kinase complexed with AZTMP and ADP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
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1E9B
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![BU of 1e9b by Molmil](/molmil-images/mine/1e9b) | Human thymidylate kinase complexed with AZTMP and APPNP | Descriptor: | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. | Deposit date: | 2000-10-10 | Release date: | 2001-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
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3I6W
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3I6U
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1FP4
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![BU of 1fp4 by Molmil](/molmil-images/mine/1fp4) | CRYSTAL STRUCTURE OF THE ALPHA-H195Q MUTANT OF NITROGENASE | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE-MO-S CLUSTER, ... | Authors: | Sorlie, M, Christiansen, J, Lemon, B.J, Peters, J.W, Dean, D.R, Hales, B.J. | Deposit date: | 2000-08-30 | Release date: | 2002-11-20 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanistic features and structure of the nitrogenase alpha-Gln195 MoFe protein Biochemistry, 40, 2001
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3J9T
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![BU of 3j9t by Molmil](/molmil-images/mine/3j9t) | Yeast V-ATPase state 1 | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Zhao, J, Benlekbir, S, Rubinstein, J.L. | Deposit date: | 2015-02-23 | Release date: | 2015-05-13 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
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3K2L
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![BU of 3k2l by Molmil](/molmil-images/mine/3k2l) | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) | Descriptor: | CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ... | Authors: | Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-30 | Release date: | 2009-10-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Structure, 21, 2013
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3J9V
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![BU of 3j9v by Molmil](/molmil-images/mine/3j9v) | Yeast V-ATPase state 3 | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Zhao, J, Benlekbir, S, Rubinstein, J.L. | Deposit date: | 2015-02-23 | Release date: | 2015-05-13 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (8.3 Å) | Cite: | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
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3J9U
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![BU of 3j9u by Molmil](/molmil-images/mine/3j9u) | Yeast V-ATPase state 2 | Descriptor: | V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... | Authors: | Zhao, J, Benlekbir, S, Rubinstein, J.L. | Deposit date: | 2015-02-23 | Release date: | 2015-05-13 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
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1GGW
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![BU of 1ggw by Molmil](/molmil-images/mine/1ggw) | |
3KVW
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![BU of 3kvw by Molmil](/molmil-images/mine/3kvw) | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand | Descriptor: | (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Authors: | Filippakopoulos, P, Myrianthopoulos, V, Kritsanida, M, Magiatis, P, Skaltsounis, A.L, Soundararajan, M, Krojer, T, Gileadi, O, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-11-30 | Release date: | 2010-01-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand To be Published
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1H6O
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![BU of 1h6o by Molmil](/molmil-images/mine/1h6o) | Dimerisation domain from human TRF1 | Descriptor: | TELOMERIC REPEAT BINDING FACTOR 1 | Authors: | Fairall, L, Chapman, L, Rhodes, D. | Deposit date: | 2001-06-20 | Release date: | 2001-09-05 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2. Mol.Cell, 8, 2001
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1H6P
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![BU of 1h6p by Molmil](/molmil-images/mine/1h6p) | Dimeristion domain from human TRF2 | Descriptor: | MAGNESIUM ION, TELOMERIC REPEAT BINDING FACTOR 2 | Authors: | Chapman, L, Fairall, L, Rhodes, D. | Deposit date: | 2001-06-20 | Release date: | 2001-09-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the Trfh Dimerization Domain of the Human Telomere Proteins Trf1 and Trf2 Mol.Cell, 8, 2001
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1HS1
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![BU of 1hs1 by Molmil](/molmil-images/mine/1hs1) | |
1HS3
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1HS8
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![BU of 1hs8 by Molmil](/molmil-images/mine/1hs8) | |
1HS2
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1HS4
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3L82
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![BU of 3l82 by Molmil](/molmil-images/mine/3l82) | X-ray Crystal structure of TRF1 and Fbx4 complex | Descriptor: | F-box only protein 4, Telomeric repeat-binding factor 1 | Authors: | Zeng, Z.X, Wang, W, Yang, Y.T, Chen, Y, Yang, X.M, Diehl, J.A, Liu, X.D, Lei, M. | Deposit date: | 2009-12-29 | Release date: | 2010-03-09 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of Selective Ubiquitination of TRF1 by SCF(Fbx4) Dev.Cell, 18, 2010
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6RML
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![BU of 6rml by Molmil](/molmil-images/mine/6rml) | Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide | Descriptor: | 53BP1, DNA topoisomerase 2-binding protein 1 | Authors: | Day, M, Oliver, A.W, Pearl, L.H. | Deposit date: | 2019-05-07 | Release date: | 2019-06-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. Elife, 8, 2019
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