6RML
Crystal structure of TOPBP1 BRCT0,1,2 in complex with a 53BP1 phosphopeptide
Summary for 6RML
Entry DOI | 10.2210/pdb6rml/pdb |
Descriptor | DNA topoisomerase 2-binding protein 1, 53BP1 (2 entities in total) |
Functional Keywords | brct domain phosphopeptide recognition, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 69538.52 |
Authors | Day, M.,Oliver, A.W.,Pearl, L.H. (deposition date: 2019-05-07, release date: 2019-06-12, Last modification date: 2024-01-24) |
Primary citation | Bigot, N.,Day, M.,Baldock, R.A.,Watts, F.Z.,Oliver, A.W.,Pearl, L.H. Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. Elife, 8:-, 2019 Cited by PubMed: 31135337DOI: 10.7554/eLife.44353 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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