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6CGX
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Backbone cyclised conotoxin Vc1.1 mutant - D11A, E14A
Descriptor: Alpha-conotoxin Vc1A
Authors:Clark, R.J.
Deposit date:2018-02-21
Release date:2018-05-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by alpha-Conotoxin Vc1.1.
ACS Chem. Biol., 13, 2018
4WHT
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Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form
Descriptor: Epitope peptide, Heavy chain of the Fab fragment derived from neutralizing antibody 3/11, Light chain of the Fab fragment derived from neutralizing antibody 3/11
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-23
Release date:2014-12-17
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
6CEJ
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Solution structure of a 14mer fragment of the p21 protein
Descriptor: Cyclin-dependent kinase inhibitor 1
Authors:Wegener, K.L.
Deposit date:2018-02-12
Release date:2018-07-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24, 2018
1QMI
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Crystal structure of RNA 3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology
Descriptor: RNA 3'-TERMINAL PHOSPHATE CYCLASE
Authors:Palm, G.J, Billy, E, Filipowicz, W, Wlodawer, A.
Deposit date:1999-09-28
Release date:2000-01-11
Last modified:2013-04-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology
Structure, 8, 2000
1QNI
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Crystal Structure of Nitrous Oxide Reductase from Pseudomonas nautica, at 2.4A Resolution
Descriptor: (MU-4-SULFIDO)-TETRA-NUCLEAR COPPER ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Brown, K, Tegoni, M, Cambillau, C.
Deposit date:1999-10-15
Release date:2000-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel type of catalytic copper cluster in nitrous oxide reductase.
Nat.Struct.Biol., 7, 2000
6YFG
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Virus-like particle of Beihai levi-like virus 32
Descriptor: CALCIUM ION, coat protein
Authors:Rumnieks, J, Kalnins, G, Sisovs, M, Lieknina, I, Tars, K.
Deposit date:2020-03-26
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.897 Å)
Cite:Three-dimensional structure of 22 uncultured ssRNA bacteriophages: Flexibility of the coat protein fold and variations in particle shapes.
Sci Adv, 6, 2020
1O7A
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Human beta-Hexosaminidase B
Descriptor: 1,2-ETHANEDIOL, 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Maier, T, Strater, N, Schuette, C, Klingenstein, R, Sandhoff, K, Saenger, W.
Deposit date:2002-10-29
Release date:2003-10-23
Last modified:2020-11-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The X-Ray Crystal Structure of Human Beta-Hexosaminidase B Provides New Insights Into Sandhoff Disease
J.Mol.Biol., 328, 2003
205D
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STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP
Descriptor: RNA (5'-R(*GP*GP*AP*CP*UP*UP*UP*GP*GP*UP*CP*C)-3')
Authors:Baeyens, K.J, De Bondt, H.L, Holbrook, S.R.
Deposit date:1995-04-14
Release date:1995-09-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structure of an RNA double helix including uracil-uracil base pairs in an internal loop.
Nat.Struct.Biol., 2, 1995
210D
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CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE
Descriptor: DNA (5'-D(*CP*GP*TP*(1AP)P*CP*G)-3'), SPERMINE
Authors:Parkinson, G.N, Arvantis, G.M, Lessinger, L, Ginell, S.L, Jones, R, Gaffney, B, Berman, H.M.
Deposit date:1995-06-13
Release date:1996-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.
Biochemistry, 34, 1995
4WY0
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PdxS (G. stearothermophilus) co-crystallized with R5P in the presence of ammonia.
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, PHOSPHATE ION, ...
Authors:Smith, J.L, Smith, A.M.
Deposit date:2014-11-14
Release date:2015-01-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.
J.Biol.Chem., 290, 2015
1N4S
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Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product
Descriptor: CHLORIDE ION, Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b, GERAN-8-YL GERAN, ...
Authors:Taylor, J.S, Reid, T.S, Casey, P.J, Beese, L.S.
Deposit date:2002-11-01
Release date:2003-11-18
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J., 22, 2003
239D
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POLYMORPHISM IN LEFT HANDED DNA: THE CRYSTAL STRUCTURE OF D(CCCGGG)2
Descriptor: DNA (5'-D(*CP*CP*CP*GP*GP*G)-3')
Authors:Karthe, P, Krishnaswamy, S, Gautham, N.
Deposit date:1995-11-02
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Polymorphism in Left Handed DNA: The Crystal Structure of d(CCCGGG)2
To be Published, 1996
1N32
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Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer RNA anticodon stem-loop mismatched at the first codon position at the a site with paromomycin
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
Deposit date:2002-10-25
Release date:2002-11-29
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002
217D
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CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Descriptor: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1995-07-18
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2, 1995
227D
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A CRYSTALLOGRAPHIC AND SPECTROSCOPIC STUDY OF THE COMPLEX BETWEEN D(CGCGAATTCGCG)2 AND 2,5-BIS(4-GUANYLPHENYL)FURAN, AN ANALOGUE OF BERENIL. STRUCTURAL ORIGINS OF ENHANCED DNA-BINDING AFFINITY
Descriptor: 2,5-BIS(4-GUANYLPHENYL)FURAN, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Laughton, C.A, Tanious, F, Nunn, C.M, Boykin, D.W, Wilson, W.D, Neidle, S.
Deposit date:1995-08-08
Release date:1995-11-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.
Biochemistry, 35, 1996
216D
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CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN
Descriptor: DISTAMYCIN A, DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3'), MAGNESIUM ION
Authors:Chen, X, Ramakrishnan, B, Sundaralingam, M.
Deposit date:1995-07-18
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2, 1995
4XI2
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Crystal Structure of an auto-inhibited form of Bruton's Tryrosine Kinase
Descriptor: GOLD ION, Tyrosine-protein kinase BTK
Authors:Vogan, E.M, Harrison, S.C.
Deposit date:2015-01-06
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.
Elife, 4, 2015
237D
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CRYSTAL STRUCTURE OF A DNA DECAMER SHOWING A NOVEL PSEUDO FOUR-WAY HELIX-HELIX JUNCTION
Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*TP*TP*GP*CP*G)-3')
Authors:Spink, N, Nunn, C.M, Vojtechovsky, J, Berman, H.M, Neidle, S.
Deposit date:1995-09-28
Release date:1996-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DNA decamer showing a novel pseudo four-way helix-helix junction.
Proc.Natl.Acad.Sci.USA, 92, 1995
1QAT
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1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA COMPLEX WITH SAMARIUM (III) CHLORIDE
Descriptor: PHOSPHOLIPASE C DELTA-1, SAMARIUM (III) ION
Authors:Grobler, J.A, Hurley, J.H.
Deposit date:1996-08-02
Release date:1997-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:C2 domain conformational changes in phospholipase C-delta 1.
Nat.Struct.Biol., 3, 1996
211D
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THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE
Descriptor: DNA (5'-D(*CP*GP*TP*(1AP)P*CP*(PT(NH3)3)G)-3'), PLATINUM TRIAMINE ION, SPERMINE
Authors:Parkinson, G.N, Arvantis, G.M, Lessinger, L, Ginell, S.L, Jones, R, Gaffney, B, Berman, H.M.
Deposit date:1995-06-13
Release date:1996-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.
Biochemistry, 34, 1995
264D
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THREE-DIMENSIONAL CRYSTAL STRUCTURE OF THE A-TRACT DNA DODECAMER D(CGCAAATTTGCG) COMPLEXED WITH THE MINOR-GROOVE-BINDING DRUG HOECHST 33258
Descriptor: 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3')
Authors:Vega, M.C, Garcia-Saez, I, Aymami, J, Eritja, R, Van Der Marel, G.A, Van Boom, J.H, Rich, A, Coll, M.
Deposit date:1994-09-22
Release date:1995-03-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Three-dimensional crystal structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor-groove-binding drug Hoechst 33258.
Eur.J.Biochem., 222, 1994
289D
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TARGETING THE MINOR GROOVE OF DNA: CRYSTAL STRUCTURES OF TWO COMPLEXES BETWEEN FURAN DERIVATIVES OF BERENIL AND THE DNA DODECAMER D(CGCGAATTCGCG)2
Descriptor: 2,5-BIS{[4-(N-CYCLOPROPYLDIAMINOMETHYL)PHENYL]}FURAN, DNA (5'-R(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Trent, J.O, Clark, G.R, Kumar, A, Wilson, W.D, Boykin, D.W, Hall, J.E, Tidwell, R.R, Blagburn, B.L, Neidle, S.
Deposit date:1996-10-10
Release date:1996-12-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
J.Med.Chem., 39, 1996
218D
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THE STRUCTURE OF A NEW CRYSTAL FORM OF A DNA DODECAMER CONTAINING T.(O6ME)G BASE PAIRS
Descriptor: DNA (5'-D(*CP*GP*TP*GP*AP*AP*TP*TP*CP*(6OG)P*CP*G)-3')
Authors:Vojtechovsky, J, Eaton, M.D, Gaffney, B, Jones, R, Berman, H.M.
Deposit date:1995-07-18
Release date:1995-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of a new crystal form of a DNA dodecamer containing T.(O6Me)G base pairs.
Biochemistry, 34, 1995
1OLX
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Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase
Descriptor: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, GLYCEROL, ...
Authors:Wynn, R.M, Machius, M, Chuang, J.L, Li, J, Tomchick, D.R, Chuang, D.T.
Deposit date:2003-08-18
Release date:2003-08-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site.
J.Biol.Chem., 278, 2003
238D
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CRYSTAL STRUCTURE OF THE DNA DECAMER D(AGG(BR)CATGCCT): COMPARISON WITH D(AGGCATGCCT) AND IMPLICATIONS FOR COBALT HEXAMMINE BINDING TO DNA
Descriptor: DNA (5'-D(*AP*GP*GP*(CBR)P*AP*TP*GP*CP*CP*T)-3')
Authors:Nunn, C.M.
Deposit date:1995-11-02
Release date:1996-01-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of d(AGGBrCATGCCT): implications for cobalt hexammine binding to DNA
J.Biomol.Struct.Dyn., 14, 1996

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