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1MJU
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1.22 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12
Descriptor: GLYCEROL, IMMUNOGLOBULIN MS6-12
Authors:Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W.
Deposit date:2002-08-28
Release date:2003-09-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.22 Å)
Cite:High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
5A7X
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negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195, ...
Authors:Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P.
Deposit date:2015-07-10
Release date:2015-08-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env.
Cell(Cambridge,Mass.), 162, 2015
8K3C
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Nipah virus Attachment glycoprotein with 41-6 antibody fragment
Descriptor: Glycoprotein G, Heavy chain of 41-6 Fab fragments, Light chain of 41-6 Fab fragment
Authors:Sun, M.M.
Deposit date:2023-07-15
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Potent human neutralizing antibodies against Nipah virus derived from two ancestral antibody heavy chains.
Nat Commun, 15, 2024
8DZV
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BU of 8dzv by Molmil
Chicken anti-cardiac Troponin I antibody in complex with peptide
Descriptor: PHOSPHATE ION, POTASSIUM ION, cTnI peptide, ...
Authors:Conroy, P.J, Law, H.P.
Deposit date:2022-08-08
Release date:2023-07-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies.
Acs Chem.Biol., 18, 2023
4AEI
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BU of 4aei by Molmil
Crystal structure of the AaHII-Fab4C1 complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALPHA-MAMMAL TOXIN AAH2, CHLORIDE ION, ...
Authors:Fabrichny, I.P, Mondielli, G, Conrod, S, Martin-Eauclaire, M.F, Bourne, Y, Marchot, P.
Deposit date:2012-01-10
Release date:2012-03-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom
J.Biol.Chem., 287, 2012
3QXU
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Free Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody
Descriptor: Anti-Methotrexate CDR1-3 Graft, FORMIC ACID
Authors:Fanning, S.W, Horn, J.R.
Deposit date:2011-03-02
Release date:2011-07-06
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Protein Sci., 20, 2011
3QXT
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Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody in Complex with Methotrexate
Descriptor: Anti-Methotrexate CDR1-3 Graft VHH, METHOTREXATE, SODIUM ION
Authors:Fanning, S.W, Horn, J.R.
Deposit date:2011-03-02
Release date:2011-07-06
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Protein Sci., 20, 2011
6VPX
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Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs
Descriptor: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rantalainen, K, Ward, A.B.W.
Deposit date:2020-02-04
Release date:2020-04-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5 Å)
Cite:HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.
Cell Rep, 31, 2020
1KFA
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Crystal structure of Fab fragment complexed with gibberellin A4
Descriptor: GIBBERELLIN A4, monoclonal antibody heavy chain, monoclonal antibody light chain
Authors:Murata, T, Fushinobu, S, Nakajima, M, Asami, O, Sassa, T, Wakagi, T, Yamaguchi, I.
Deposit date:2001-11-20
Release date:2002-09-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the liganded anti-gibberellin A(4) antibody 4-B8(8)/E9 Fab fragment.
Biochem.Biophys.Res.Commun., 293, 2002
3QXW
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Free structure of an anti-methotrexate CDR1-4 Graft VHH Antibody
Descriptor: Anti-Methotrexate CDR1-4 Graft VHH, SODIUM ION, SULFATE ION
Authors:Fanning, S.W, Horn, J.R.
Deposit date:2011-03-02
Release date:2011-07-27
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop.
Protein Sci., 20, 2011
1MJ7
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Crystal Structure Of The Complex Of The Fab fragment of Esterolytic Antibody MS5-393 and A Transition-State Analog
Descriptor: IMMUNOGLOBULIN MS5-393, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE
Authors:Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W.
Deposit date:2002-08-27
Release date:2003-09-23
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
5BZD
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BU of 5bzd by Molmil
Crystal Structure of PCDN-27A, an antibody from the PCDN family of HIV-1 antibodies
Descriptor: 5G8 HIV Antibody heavy chain, 5G8 HIV Antibody light chain, GLYCEROL
Authors:Garces, F, WILSON, I.A.
Deposit date:2015-06-11
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch
Immunity, 44, 2016
3GKZ
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BU of 3gkz by Molmil
Crystal structures of a therapeutic single chain antibody in complex methamphetamine
Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, anti-methamphetamine single chain Fv
Authors:Celikel, R, Peterson, E.C, Owens, M, Varughese, K.I.
Deposit date:2009-03-11
Release date:2009-10-06
Last modified:2019-09-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Protein Sci., 18, 2009
1IL1
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BU of 1il1 by Molmil
Crystal structure of G3-519, an anti-HIV monoclonal antibody
Descriptor: monoclonal antibody G3-519 (heavy chain), monoclonal antibody G3-519 (light chain)
Authors:Berry, M.B, Johnson, K.A, Radding, W, Fung, M, Liou, R, Phillips Jr, G.N.
Deposit date:2001-05-07
Release date:2001-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of an anti-HIV monoclonal Fab antibody fragment specific to a gp120 C-4 region peptide.
Proteins, 45, 2001
3RA7
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BU of 3ra7 by Molmil
Bispecific digoxigenin binding antibodies for targeted payload delivery
Descriptor: DIGOXIGENIN, Fab fragment, heavy chain, ...
Authors:Hopfner, K.P, Lammens, A.
Deposit date:2011-03-27
Release date:2011-07-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Bispecific digoxigenin-binding antibodies for targeted payload delivery
Proc.Natl.Acad.Sci.USA, 108, 2011
1T4K
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BU of 1t4k by Molmil
Crystal Structure of Unliganded Aldolase Antibody 93F3 Fab
Descriptor: IMMUNOGLOBULIN IGG1, HEAVY CHAIN, KAPPA LIGHT CHAIN, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2004-04-29
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Origin of Enantioselectivity in Aldolase Antibodies: Crystal Structure, Site-directed Mutagenesis, and Computational Analysis
J.Mol.Biol., 343, 2004
8W0V
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BU of 8w0v by Molmil
Crystal structure of broadly neutralizing antibody hcab55 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W0X
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Crystal structure of broadly neutralizing antibody hcab40 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W0Y
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BU of 8w0y by Molmil
Crystal structure of broadly neutralizing antibody hcab17 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
8W0W
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BU of 8w0w by Molmil
Crystal structure of broadly neutralizing antibody hcab64 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
Authors:Flyak, A.I, Wilcox, X.E.
Deposit date:2024-02-14
Release date:2024-03-27
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance.
Immunity, 57, 2024
1BBD
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BU of 1bbd by Molmil
THREE DIMENSIONAL STRUCTURE OF THE FAB FRAGMENT OF A NEUTRALIZING ANTIBODY TO HUMAN RHINOVIRUS SEROTYPE 2
Descriptor: IGG2A-KAPPA 8F5 FAB (HEAVY CHAIN), IGG2A-KAPPA 8F5 FAB (LIGHT CHAIN), SULFATE ION
Authors:Tormo, J, Blaas, D, Fita, I.
Deposit date:1992-05-05
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Three-dimensional structure of the Fab fragment of a neutralizing antibody to human rhinovirus serotype 2.
Protein Sci., 1, 1992
4BH8
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BU of 4bh8 by Molmil
CRYSTAL STRUCTURE OF GERMLINE ANTIBODY 36-65 IN COMPLEX WITH PEPTIDE GDPRPSYISHLL
Descriptor: ANTI-ARS MURINE GERMLINE MONOCLONAL ANTIBODY 36-65, DODECAPEPTIDE ANTIGEN
Authors:Khan, T, Salunke, D.M.
Deposit date:2013-03-30
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Adjustable Locks and Flexible Keys: Plasticity of Epitope-Paratope Interactions in Germline Antibodies.
J.Immunol., 192, 2014
1H8N
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BU of 1h8n by Molmil
Three-dimensional structure of anti-ampicillin single chain Fv fragment from phage-displayed murine antibody libraries
Descriptor: GLYCEROL, MUTANT AL2 6E7S9G, SULFATE ION
Authors:Jung, S, Spinelli, S, Schimmele, B, Honegger, A, Pugliese, L, Cambillau, C, Pluckthun, A.
Deposit date:2001-02-14
Release date:2001-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Importance of Framework Residues H6, H7 and H10 in Antibody Heavy Chains: Experimental Evidence for a New Structural Subclassification of Antibody V(H) Domains
J.Mol.Biol., 309, 2001
1BAF
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BU of 1baf by Molmil
2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN
Descriptor: IGG1-KAPPA AN02 FAB (HEAVY CHAIN), IGG1-KAPPA AN02 FAB (LIGHT CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE
Authors:Leahy, D.J, Brunger, A.T, Fox, R.O, Hynes, T.R.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
6ZDH
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BU of 6zdh by Molmil
SARS-CoV-2 Spike glycoprotein in complex with a neutralizing antibody EY6A Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EY6A heavy chain, ...
Authors:Duyvesteyn, H.M.E, Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I.
Deposit date:2020-06-14
Release date:2020-07-01
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient.
Nat.Struct.Mol.Biol., 27, 2020

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