3QXU

Free Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody

Summary for 3QXU

Entry DOI	10.2210/pdb3qxu/pdb
Related	1I3U 2x6m
Descriptor	Anti-Methotrexate CDR1-3 Graft, FORMIC ACID (3 entities in total)
Functional Keywords	camelid single domain antibody, heavy chain only, vhh, antibody, anti-hapten antibody, cdr, hapten binding, small molecule sensing, ligand binding, low molecular weight compound, methotrexate, cdr1, cdr4, immune system
Biological source	Lama Glama (Llama)
Total number of polymer chains	4
Total formula weight	55176.83
Authors	Fanning, S.W.,Horn, J.R. (deposition date: 2011-03-02, release date: 2011-07-06, Last modification date: 2013-09-11)
Primary citation	Fanning, S.W.,Horn, J.R. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci., 20:1196-1207, 2011 Cited by PubMed: 21557375 DOI: 10.1002/pro.648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation