3QXU
Free Structure of an Anti-Methotrexate CDR1-3 Graft VHH Antibody
Summary for 3QXU
Entry DOI | 10.2210/pdb3qxu/pdb |
Related | 1I3U 2x6m |
Descriptor | Anti-Methotrexate CDR1-3 Graft, FORMIC ACID (3 entities in total) |
Functional Keywords | camelid single domain antibody, heavy chain only, vhh, antibody, anti-hapten antibody, cdr, hapten binding, small molecule sensing, ligand binding, low molecular weight compound, methotrexate, cdr1, cdr4, immune system |
Biological source | Lama Glama (Llama) |
Total number of polymer chains | 4 |
Total formula weight | 55176.83 |
Authors | Fanning, S.W.,Horn, J.R. (deposition date: 2011-03-02, release date: 2011-07-06, Last modification date: 2013-09-11) |
Primary citation | Fanning, S.W.,Horn, J.R. An anti-hapten camelid antibody reveals a cryptic binding site with significant energetic contributions from a nonhypervariable loop. Protein Sci., 20:1196-1207, 2011 Cited by PubMed: 21557375DOI: 10.1002/pro.648 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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