4AEI

Crystal structure of the AaHII-Fab4C1 complex

Summary for 4AEI

Entry DOI	10.2210/pdb4aei/pdb
Related	1AHO 1PTX 1SEG 4AEH
Descriptor	ALPHA-MAMMAL TOXIN AAH2, FAB ANTIBODY HEAVY CHAIN, FAB ANTIBODY LIGHT CHAIN, ... (6 entities in total)
Functional Keywords	immune system-toxin complex, alpha-toxin, conformational rearrangement, combining site, epitope, pharmacological site, venom, voltage-activated sodium channel, immune system/toxin
Biological source	ANDROCTONUS AUSTRALIS HECTOR (FAT-TAILED SCORPION) More
Cellular location	Secreted: P01484
Total number of polymer chains	9
Total formula weight	169166.50
Authors	Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P. (deposition date: 2012-01-10, release date: 2012-03-07, Last modification date: 2023-12-20)
Primary citation	Fabrichny, I.P.,Mondielli, G.,Conrod, S.,Martin-Eauclaire, M.F.,Bourne, Y.,Marchot, P. Structural Insights Into Antibody Sequestering and Neutralizing of Na+-Channel & [Alpha]-Type Modulator from Old-World Scorpion Venom J.Biol.Chem., 287:14136-, 2012 Cited by PubMed: 22371498 DOI: 10.1074/JBC.M111.315382 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation