2J1W
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2PE5
| Crystal Structure of the Lac Repressor bound to ONPG in repressed state | Descriptor: | 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor | Authors: | Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M. | Deposit date: | 2007-04-02 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural analysis of lac repressor bound to allosteric effectors J.Mol.Biol., 370, 2007
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3O3K
| Crystal structure of AF1382 from Archaeoglobus fulgidus | Descriptor: | Uncharacterized protein AF_1382 | Authors: | Zhu, J.-Y, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Xu, H, Chen, L, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2010-07-24 | Release date: | 2010-08-04 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the Archaeoglobus fulgidus orphan ORF AF1382 determined by sulfur SAD from a moderately diffracting crystal. Acta Crystallogr.,Sect.D, 68, 2012
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4LFU
| Crystal structure of Escherichia coli SdiA in the space group C2 | Descriptor: | CHLORIDE ION, Regulatory protein SdiA, TETRAETHYLENE GLYCOL | Authors: | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | Deposit date: | 2013-06-27 | Release date: | 2014-03-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor Acta Crystallogr.,Sect.D, 70, 2014
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4LGW
| Crystal structure of Escherichia coli SdiA in the space group P6522 | Descriptor: | GLYCEROL, Regulatory protein SdiA | Authors: | Kim, T, Duong, T, Wu, C.A, Choi, J, Lan, N, Kang, S.W, Lokanath, N.K, Shin, D, Hwang, H.Y, Kim, K.K. | Deposit date: | 2013-06-28 | Release date: | 2014-03-19 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the molecular mechanism of Escherichia coli SdiA, a quorum-sensing receptor Acta Crystallogr.,Sect.D, 70, 2014
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1M0I
| Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site | Descriptor: | SULFATE ION, endodeoxyribonuclease I | Authors: | Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M. | Deposit date: | 2002-06-13 | Release date: | 2002-12-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I Embo J., 21, 2002
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5LY0
| Crystal structure of LOB domain of Ramosa2 from Wheat | Descriptor: | LOB family transfactor Ramosa2.1, ZINC ION | Authors: | Wei, X.-B, Zhang, B, Chen, W.-F, Fan, S.-H, Rety, S, Xi, X.-G. | Deposit date: | 2016-09-23 | Release date: | 2017-10-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.877 Å) | Cite: | Structural analysis reveals a "molecular calipers" mechanism for a LATERAL ORGAN BOUNDARIES DOMAIN transcription factor protein from wheat. J. Biol. Chem., 294, 2019
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5MBV
| Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD. | Descriptor: | Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | Authors: | Wilkinson, M, Chaban, Y, Wigley, D.B. | Deposit date: | 2016-11-08 | Release date: | 2017-01-11 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones. Elife, 5, 2016
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5LJ4
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1M0D
| Crystal Structure of Bacteriophage T7 Endonuclease I with a Wild-Type Active Site and Bound Manganese Ions | Descriptor: | Endodeoxyribonuclease I, MANGANESE (II) ION, SULFATE ION | Authors: | Hadden, J.M, Declais, A.C, Phillips, S.E, Lilley, D.M. | Deposit date: | 2002-06-12 | Release date: | 2002-07-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I. EMBO J., 21, 2002
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4TV7
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5LRR
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione | Descriptor: | GLUTATHIONE, HYDROGENPHOSPHATE ION, Listeriolysin positive regulatory factor A, ... | Authors: | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | Deposit date: | 2016-08-19 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.171 Å) | Cite: | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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4F8D
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4K2E
| HlyU from Vibrio cholerae N16961 | Descriptor: | Transcriptional activator HlyU | Authors: | Mukherjee, D, Datta, A.B, Chakrabarti, P. | Deposit date: | 2013-04-09 | Release date: | 2014-04-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of HlyU, the hemolysin gene transcription activator, from Vibrio cholerae N16961 and functional implications. Biochim.Biophys.Acta, 1844, 2014
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3D1N
| Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter | Descriptor: | 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ... | Authors: | Pereira, J.H, Ha, S.C, Kim, S.-H. | Deposit date: | 2008-05-06 | Release date: | 2009-05-26 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structure of human Brn-5 transcription factor in complex with CRH gene promoter. J.Struct.Biol., 167, 2009
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4FBI
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4FN3
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4HK1
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3FBR
| structure of HipA-amppnp-peptide | Descriptor: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase toxin HipA, peptide of EF-Tu | Authors: | Schumacher, M.A. | Deposit date: | 2008-11-19 | Release date: | 2009-02-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
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3C3W
| Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR | Descriptor: | SULFATE ION, TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR | Authors: | Wisedchaisri, G, Wu, M, Sherman, D.R, Hol, W.G.J. | Deposit date: | 2008-01-28 | Release date: | 2008-04-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation J.Mol.Biol., 378, 2008
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4DBV
| GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH LEU 33 REPLACED BY THR, THR 34 REPLACED BY GLY, ASP 36 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NADP+ | Descriptor: | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | Authors: | Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A. | Deposit date: | 1997-01-06 | Release date: | 1997-07-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+. J.Mol.Biol., 268, 1997
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2G7O
| Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM | Descriptor: | Protein traM | Authors: | Lu, J, Edwards, R.A, Wong, J.J, Manchak, J, Scott, P.G, Frost, L.S, Glover, J.N. | Deposit date: | 2006-02-28 | Release date: | 2006-06-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Protonation-mediated structural flexibility in the F conjugation regulatory protein, TraM. Embo J., 25, 2006
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6DXL
| Linked amidobenzimidazole STING agonist | Descriptor: | 1,1'-(butane-1,4-diyl)bis{2-[(1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)amino]-1H-benzimidazole-5-carboxamide}, CALCIUM ION, Stimulator of interferon protein | Authors: | Concha, N.O. | Deposit date: | 2018-06-29 | Release date: | 2018-11-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature, 564, 2018
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2J6W
| R164N mutant of the RUNX1 Runt domain | Descriptor: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | Authors: | Grembecka, J, Zhe, L, Lukasik, S.M, Liu, Y, Bielnicka, I, Bushweller, J.H, Speck, N.A. | Deposit date: | 2006-10-04 | Release date: | 2007-10-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Mutation in the S-Switch Region of the Runt Domain Alters the Dynamics of an Allosteric Network Responsible for Cbfbeta Regulation. J.Mol.Biol., 364, 2006
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3DNT
| structures of MDT proteins | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein hipA, ... | Authors: | Schumacher, M.A. | Deposit date: | 2008-07-02 | Release date: | 2009-01-27 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009
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