3C3W
Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR
Summary for 3C3W
Entry DOI | 10.2210/pdb3c3w/pdb |
Related | 1zlj 1zlk |
Descriptor | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR, SULFATE ION (3 entities in total) |
Functional Keywords | response regulator, two-component regulatory system, dna-binding protein, tuberculosis, transcription, transcription regulation |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm (Probable): P95193 |
Total number of polymer chains | 2 |
Total formula weight | 48888.42 |
Authors | Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G.J. (deposition date: 2008-01-28, release date: 2008-04-22, Last modification date: 2024-04-03) |
Primary citation | Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G. Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation J.Mol.Biol., 378:227-242, 2008 Cited by PubMed: 18353359DOI: 10.1016/j.jmb.2008.02.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report