3C3W

Crystal Structure of the Mycobacterium tuberculosis Hypoxic Response Regulator DosR

Summary for 3C3W

• Entry DOI: 10.2210/pdb3c3w/pdb
• Related: 1zlj 1zlk
• Descriptor: TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR, SULFATE ION (3 entities in total)
• Functional Keywords: response regulator, two-component regulatory system, dna-binding protein, tuberculosis, transcription, transcription regulation
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm (Probable): P95193
• Total number of polymer chains: 2
• Total formula weight: 48888.42

Authors

Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G.J. (deposition date: 2008-01-28, release date: 2008-04-22, Last modification date: 2024-04-03)

• Primary citation: Wisedchaisri, G.,Wu, M.,Sherman, D.R.,Hol, W.G.; Crystal structures of the response regulator DosR from Mycobacterium tuberculosis suggest a helix rearrangement mechanism for phosphorylation activation; J.Mol.Biol., 378:227-242, 2008; PubMed: 18353359; DOI: 10.1016/j.jmb.2008.02.029

Experimental method

X-RAY DIFFRACTION (2.2 Å)