7O4P
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![BU of 7o4p by Molmil](/molmil-images/mine/7o4p) | Cystal structure of Zymogen Granule Protein 16 (ZG16) | Descriptor: | CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16 | Authors: | Javitt, G, Fass, D. | Deposit date: | 2021-04-07 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | Conformational switches and redox properties of the colon cancer-associated human lectin ZG16. Febs J., 288, 2021
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7O3I
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![BU of 7o3i by Molmil](/molmil-images/mine/7o3i) | Cystal structure of Zymogen Granule Protein 16 (ZG16) | Descriptor: | CHLORIDE ION, GLYCEROL, Zymogen granule membrane protein 16 | Authors: | Javitt, G, Fass, D. | Deposit date: | 2021-04-01 | Release date: | 2021-06-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Conformational switches and redox properties of the colon cancer-associated human lectin ZG16. Febs J., 288, 2021
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7O88
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7O2C
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![BU of 7o2c by Molmil](/molmil-images/mine/7o2c) | X-RAY STRUCTURE OF SMYD3 IN COMPLEX WITH the benzodiazepine-based probe BAY-6035 | Descriptor: | (2S)-1-[[(1R,5S)-3-azabicyclo[3.1.0]hexan-3-yl]carbonyl]-N-(2-cyclopropylethyl)-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | Authors: | Steuber, H. | Deposit date: | 2021-03-30 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Slas Discov, 26, 2021
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7ODH
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7OC5
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![BU of 7oc5 by Molmil](/molmil-images/mine/7oc5) | Alpha-humulene synthase AsR6 from Sarocladium schorii | Descriptor: | Alpha-humulene synthase AsR6, MAGNESIUM ION, ZINC ION | Authors: | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | Deposit date: | 2021-04-26 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Understanding and Engineering the Stereoselectivity of Humulene Synthase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7NWO
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![BU of 7nwo by Molmil](/molmil-images/mine/7nwo) | A carbohydrate binding module family 9 (CBM9) from Caldicellulosiruptor kristjanssonii in complex with glucose | Descriptor: | 1,2-ETHANEDIOL, Beta-xylanase, CALCIUM ION, ... | Authors: | Krska, D, Mazurkewich, S, Navarro Poulsen, J, Larsbrink, J, Lo Leggio, L. | Deposit date: | 2021-03-17 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Functional Analysis of a Multimodular Hyperthermostable Xylanase-Glucuronoyl Esterase from Caldicellulosiruptor kristjansonii . Biochemistry, 60, 2021
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7O2A
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![BU of 7o2a by Molmil](/molmil-images/mine/7o2a) | X-RAY STRUCTURE OF SMYD3 IN COMPLEX WITH benzodiazepine-type inhibitor compound 15 | Descriptor: | (2S)-1-(4-azanylpiperidin-1-yl)carbonyl-N-(2-cyclopropylethyl)-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | Authors: | Steuber, H. | Deposit date: | 2021-03-30 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Slas Discov, 26, 2021
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7OC6
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![BU of 7oc6 by Molmil](/molmil-images/mine/7oc6) | Selenomethionine derivative of alpha-humulene synthase AsR6 from Sarocladium schorii | Descriptor: | Alpha-humulene synthase asR6, GLYCEROL, SULFATE ION, ... | Authors: | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | Deposit date: | 2021-04-26 | Release date: | 2021-07-07 | Last modified: | 2021-09-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Understanding and Engineering the Stereoselectivity of Humulene Synthase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7OG7
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![BU of 7og7 by Molmil](/molmil-images/mine/7og7) | Crystal structure of the copper chaperone NosL from Shewanella denitrificans | Descriptor: | ACETONITRILE, COPPER (I) ION, NosL, ... | Authors: | Prasser, B, Schoener, L, Zhang, L, Einsle, O. | Deposit date: | 2021-05-06 | Release date: | 2021-07-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Copper Chaperone NosL Forms a Heterometal Site for Cu Delivery to Nitrous Oxide Reductase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7O2B
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![BU of 7o2b by Molmil](/molmil-images/mine/7o2b) | X-RAY STRUCTURE OF SMYD3 in complex with benzodiazepine-type inhibitor 6 | Descriptor: | (2S)-N-butyl-1-(2-fluorophenyl)carbonyl-2-methyl-4-oxidanylidene-3,5-dihydro-2H-1,5-benzodiazepine-7-carboxamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | Authors: | Steuber, H. | Deposit date: | 2021-03-30 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Discovery of the SMYD3 Inhibitor BAY-6035 Using Thermal Shift Assay (TSA)-Based High-Throughput Screening. Slas Discov, 26, 2021
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7ODG
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7OC4
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![BU of 7oc4 by Molmil](/molmil-images/mine/7oc4) | Alpha-humulene synthase AsR6 from Sarocladium schorii in complex with thiolodiphosphate and a cyclized reaction product. | Descriptor: | (1E,4E,8E)-2,6,6,9-Tetramethyl-1,4-8-cycloundecatriene, (R,R)-2,3-BUTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J. | Deposit date: | 2021-04-26 | Release date: | 2021-07-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Understanding and Engineering the Stereoselectivity of Humulene Synthase. Angew.Chem.Int.Ed.Engl., 60, 2021
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3JPW
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![BU of 3jpw by Molmil](/molmil-images/mine/3jpw) | Crystal structure of amino terminal domain of the NMDA receptor subunit NR2B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glutamate [NMDA] receptor subunit epsilon-2, ... | Authors: | Karakas, E, Simorowski, N, Furukawa, H. | Deposit date: | 2009-09-04 | Release date: | 2009-12-08 | Last modified: | 2021-10-13 | Method: | X-RAY DIFFRACTION (2.803 Å) | Cite: | Structure of the zinc-bound amino-terminal domain of the NMDA receptor NR2B subunit. Embo J., 28, 2009
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3BXM
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![BU of 3bxm by Molmil](/molmil-images/mine/3bxm) | Structure of an inactive mutant of human glutamate carboxypeptidase II [GCPII(E424A)] in complex with N-acetyl-Asp-Glu (NAAG) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Lubkowski, J, Barinka, C. | Deposit date: | 2008-01-14 | Release date: | 2009-01-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods. Biochemistry, 48, 2009
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4UV7
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![BU of 4uv7 by Molmil](/molmil-images/mine/4uv7) | The complex structure of extracellular domain of EGFR and GC1118A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | Authors: | Yoo, J.H, Cho, H.S. | Deposit date: | 2014-08-05 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Gc1118, an Anti-Egfr Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity Against High-Affinity Egfr Ligands. Mol.Cancer Ther., 15, 2016
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7NSH
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![BU of 7nsh by Molmil](/molmil-images/mine/7nsh) | 39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2 | Descriptor: | 16S rRNA, 39S ribosomal protein L48, mitochondrial, ... | Authors: | Kummer, E, Schubert, K, Ban, N. | Deposit date: | 2021-03-07 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
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7O1H
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7OEV
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7NVY
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![BU of 7nvy by Molmil](/molmil-images/mine/7nvy) | RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | Descriptor: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NSY
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![BU of 7nsy by Molmil](/molmil-images/mine/7nsy) | Drosophila PGRP-LB C160S mutant | Descriptor: | Isoform A of Peptidoglycan-recognition protein LB | Authors: | Orlans, J, Aller, P, Da Silva, P. | Deposit date: | 2021-03-08 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | PGRP-LB: An Inside View into the Mechanism of the Amidase Reaction. Int J Mol Sci, 22, 2021
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7NSZ
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![BU of 7nsz by Molmil](/molmil-images/mine/7nsz) | Drosophila PGRP-LB Y78F mutant | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Isoform A of Peptidoglycan-recognition protein LB, SODIUM ION, ... | Authors: | Orlans, J, Aller, P, Da Silva, P. | Deposit date: | 2021-03-08 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | PGRP-LB: An Inside View into the Mechanism of the Amidase Reaction. Int J Mol Sci, 22, 2021
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7NUQ
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![BU of 7nuq by Molmil](/molmil-images/mine/7nuq) | Rhinovirus 14 virion-like at pH 6.2 | Descriptor: | Genome polyprotein, Octanucleotide | Authors: | Hrebik, D, Plevka, P. | Deposit date: | 2021-03-12 | Release date: | 2021-05-19 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating. Proc.Natl.Acad.Sci.USA, 118, 2021
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7OEN
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7NUN
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![BU of 7nun by Molmil](/molmil-images/mine/7nun) | Rhinovirus 14 ICAM-1 virion-like particle at pH 6.2 | Descriptor: | Genome polyprotein, Octanucleotide | Authors: | Hrebik, D, Plevka, P. | Deposit date: | 2021-03-12 | Release date: | 2021-05-19 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating. Proc.Natl.Acad.Sci.USA, 118, 2021
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