4DQV

Crystal structure of reductase (R) domain of non-ribosomal peptide synthetase from Mycobacterium tuberculosis

Summary for 4DQV

• Entry DOI: 10.2210/pdb4dqv/pdb
• Descriptor: PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) (2 entities in total)
• Functional Keywords: gxxgxxg motif, rossmann fold, short chain dehydrogenase/reductase family, reductase, lipopeptide, ligase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 52725.95

Authors

Haque, A.S.,Panjikar, S.,Sankaranarayanan, R. (deposition date: 2012-02-16, release date: 2012-06-20, Last modification date: 2017-11-15)

• Primary citation: Chhabra, A.,Haque, A.S.,Pal, R.K.,Goyal, A.,Rai, R.,Joshi, S.,Panjikar, S.,Pasha, S.,Sankaranarayanan, R.,Gokhale, R.S.; Nonprocessive [2 + 2]e- off-loading reductase domains from mycobacterial nonribosomal peptide synthetases.; Proc.Natl.Acad.Sci.USA, 109:5681-5686, 2012; PubMed: 22451903; DOI: 10.1073/pnas.1118680109

Experimental method